| Identification | Back Directory | [Name]
N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER | [CAS]
135042-17-0 | [Synonyms]
Boc-trans-D-Hyp-OMe
Boc-D-trans-Hyp-OMe
trans-Boc-D-Hpy-Ome
N-Boc-trans-D-Hyp-Ome
(Tert-Butoxy)Carbonyl D-trans-Hyp-OMe
Methyl (4S)-1-Boc-4-hydroxy-D-prolinate
Boc-trans-4-Hydroxy-D-proline Methyl ester
N-Boc-Trans-4-Hydroxy-D-Proline Methyl Este
(2R,4S)-N-Boc-4-hydroxyproline methyl ester
N-Boc-Trans-5-Hydroxy-D-Proline Methyl Ester
N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
(2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4S)-N-Boc-trans-4-hydroxy-D-proline methyl ester
N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER USP/EP/BP
Methyl (2R,4S)-1-Boc-4-hydroxypyrrolidine-2-carboxylate
N-tert-butoxycarbonyl-trans-4-hydroxy-D-proline Methyl ester
N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER (CAS NO.135042-17-0)
(2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
1-tert-butyl 2-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
1-O-tert-butyl 2-O-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl
(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2R,4S)-
(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-Methyl ester (N-Boc-trans-4-Hydroxy-D-proline Methyl ester | [EINECS(EC#)]
828-101-2 | [Molecular Formula]
C11H19NO5 | [MDL Number]
MFCD09954932 | [MOL File]
135042-17-0.mol | [Molecular Weight]
245.28 |
| Chemical Properties | Back Directory | [Boiling point ]
335.2±42.0 °C(Predicted) | [density ]
1.216±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
14.27±0.40(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m0/s1 | [InChIKey]
MZMNEDXVUJLQAF-JGVFFNPUSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)C[C@@H](O)C[C@@H]1C(OC)=O | [CAS DataBase Reference]
135042-17-0 |
| Hazard Information | Back Directory | [Uses]
N-Boc-Trans-4-Hydroxy-D-proline methyl ester is a valuable organic compound that could be used to synthesis 1-tert-Butyl 2-methyl (2R)-4-oxopyrrolidine-1,2-dicarboxylate.
| [Application]
N-Boc-Trans-4-Hydroxy-D-proline methyl ester is mainly used as a chiral building block in drug development and organic synthesis, especially as a non-cleaving linker in the synthesis of antibody-drug conjugates (ADCs), and plays a key role in proteomics research, peptide synthesis and the development of complex bioactive molecules. | [IC 50]
Non-cleavable Linker |
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