| Identification | Back Directory | [Name]
2-{3-[2-(1-{2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate | [CAS]
1360819-11-9 | [Synonyms]
2-{3-[2-(1-{2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate
Ethanone, 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-[4-[5-[2-chloro-6-[(methylsulfonyl)oxy]phenyl]-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]- | [EINECS(EC#)]
810-160-0 | [Molecular Formula]
C25H24ClF4N5O5S2 | [MOL File]
1360819-11-9.mol | [Molecular Weight]
650.07 |
| Hazard Information | Back Directory | [Definition]
ChEBI: 2-[(ethanesulfonyl)amino]-5-fluoro-4-[4-methyl-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]benzene-1-carbothioamide is a member of the class of 1,3-thiazoles that is 4-(1,3-thiazol-2-yl)piperidine in which the piperidine amino group is substituted by a [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl group and position 4 of the thiazole ring is substituted by a 5-{2-chloro-6-[(methylsulfonyl)oxy]phenyl}-4,5-dihydro-1,2-oxazol-3-yl group. It is an organofluorine compound, a member of 1,3-thiazoles, a N-acylpiperidine, an isoxazoline, a member of pyrazoles, a tertiary carboxamide, a member of monochlorobenzenes and a methanesulfonate ester. | [Production Methods]
Fluoxapiprolin is produced through a multi-step industrial synthesis typical of modern piperidinyl-amide fungicides, combining tightly controlled heterocycle construction with late stage functionalisation to achieve the molecule’s distinctive diaryl-substituted piperidine core. Commercial routes begin with preparation of the substituted piperidine scaffold, usually via catalytic hydrogenation or reductive amination of a protected precursor, followed by introduction of the difluoro- and chloro-substituted aromatic rings through sequential coupling reactions under anhydrous, high-purity conditions. The amide linkage is then formed by reacting the activated carboxylic acid derivative with the piperidinyl intermediate, often using carbodiimide or mixed-anhydride chemistry optimised for scale. | [Mechanism of action]
Oxysterol-binding protein homologue inhibition (OSBPI). | [Pesticide Type]
Fungicide |
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