| Identification | Back Directory | [Name]
2'-Fluoro-2'-deoxy-ara-C-3'-phosphoramidite | [CAS]
1404463-12-2 | [Synonyms]
2'-F-2'-ara-Bz-dC Phosphoramidite
2'-F-dC(Bz)-ANA-CE Phosphoramidite
2'-F-2'-ara-N4-Bz-dC phosphoramidite
2'-Fluoro-2'-deoxy-ara-C-3'-phosphoramidite
’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite
5'-O-DMT-2'-Fluoro-N4-Benzoyl-2'-arabinofuranosyl-2'-deoxycytidine phosphoramidite
1-[2-DEOXY-2-FLUORO-5-O-DMTr-Β-D- ARABINOFURANOSYL]-N4-BENZOYL-CYTOSINE-3-O-CE-AMIDITE
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro--D-arabinouridine-3'-CED-phosphoramidite
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine-3'-CEN-phosphoramidite
5'-Dimethoxytrityl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine 3'-[(2-cyanoethyl)-(N, N-diisopropyl)]-phosphoramidite
Benzamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]- | [Molecular Formula]
C46H51FN5O8P | [MOL File]
1404463-12-2.mol | [Molecular Weight]
851.91 |
| Chemical Properties | Back Directory | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml | [form ]
Solid | [pka]
8.50±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. | [References]
[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308 |
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