1446282-44-5

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1446282-44-5 Structure

Identification	Back Directory
[Name] Bromo-PEG2-phosphonic acid
[CAS] 1446282-44-5
[Synonyms] Bromo-PEG2-phosphonic acid Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-
[Molecular Formula] C6H14BrO5P
[MDL Number] MFCD25424120
[MOL File] 1446282-44-5.mol
[Molecular Weight] 277.05

Hazard Information	Back Directory
[Description] Bromo-PEG2-phosphonic acid is a PEG linker containing bromine and phosphonic acid moieties. The bromine group is a good leaving group and participates in substiution reactions. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
[Uses] Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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