| Identification | Back Directory | [Name]
Bromo-PEG2-phosphonic acid | [CAS]
1446282-44-5 | [Synonyms]
Bromo-PEG2-phosphonic acid
Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]- | [Molecular Formula]
C6H14BrO5P | [MDL Number]
MFCD25424120 | [MOL File]
1446282-44-5.mol | [Molecular Weight]
277.05 |
| Hazard Information | Back Directory | [Description]
Bromo-PEG2-phosphonic acid is a PEG linker containing bromine and phosphonic acid moieties. The bromine group is a good leaving group and participates in substiution reactions. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. | [Uses]
Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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