| Identification | More | [Name]
1-Methyl-aminomethyl naphthalene | [CAS]
14489-75-9 | [Synonyms]
1-METHYL-1-NAPHTHALENEMETHYLAMINE
1-(METHYLAMINOMETHYL)NAPHTHALENE
AURORA KA-7760
N-METHYL-1-NAPHTHALENEMETHYLAMINE
N-METHYL-1-NAPHTHYLMETHYLAMINE
N-METHYLNAPHTHALENE-1-METHYLAMINE
N-METHYL NAPHTHYLMETHYLAMINE
TIMTEC-BB SBB005765
(1-Naphthylmethyl)Methylamine Hydrochloride
1-(1-naphthalenyl)methylamine
N-methyl hydrochloric salt
1-Naphthalenemethanamine, N-methyl-
N-METHYL-1-NAPHTHYLETHYL AMINE
1-methyl-aminomethyl-1-naphthalene
1-[(Methylamino)-methyl]-naphtalene
N-methyl-1-menaphthylamine
N-METHYL-1-NAPHTHALENEAMINE
N-(1-Naphtylmethyl)-N-methylamine
N-Methyl(1-naphtyl)methaneamine
N-Methyl-1-naphtylmethanamine | [EINECS(EC#)]
238-497-3 | [Molecular Formula]
C12H13N | [MDL Number]
MFCD00144934 | [Molecular Weight]
171.24 | [MOL File]
14489-75-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
189.5-190 °C | [Boiling point ]
104 °C | [density ]
1,05 g/cm3 | [refractive index ]
1.6160-1.6190 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
clear liquid | [pka]
9.38±0.10(Predicted) | [color ]
Colorless to Orange to Green | [PH]
10.71 at 24℃ and 10g/L | [InChI]
InChI=1S/C12H13N/c1-13-9-11-7-4-6-10-5-2-3-8-12(10)11/h2-8,13H,9H2,1H3 | [InChIKey]
MQRIUFVBEVFILS-UHFFFAOYSA-N | [SMILES]
C1(CNC)=C2C(C=CC=C2)=CC=C1 | [CAS DataBase Reference]
14489-75-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [HS Code ]
2921.49.5000 | [HazardClass ]
IRRITANT |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Oil | [Synthesis]
The crude product N-methyl-N-(1-naphthylmethyl)formamide prepared according to step (a) was suspended in 300 mL of 20% aqueous sodium hydroxide solution and the reaction was heated at 60-70°C for 7 hours. Upon completion of the reaction, the mixture was cooled to 25 °C and subsequently extracted with toluene (2 x 200 mL). The toluene extracts were combined and back-extracted with 3N hydrochloric acid (2 x 300 mL). The aqueous phase was decolorized with activated carbon and the pH was adjusted with 20% aqueous sodium hydroxide to 10.0. The released free base was extracted with toluene, and the toluene layers were combined and distilled to remove the solvent to give 86 g of crude product. Finally, 82 g (85% yield) of pure N-methyl-1-naphthalenemethylamine was obtained by high vacuum distillation purification. | [References]
[1] Patent: WO2004/80945, 2004, A1. Location in patent: Page 8
[2] Patent: WO2004/80945, 2004, A1. Location in patent: Page 9-10 |
| Questions And Answer | Back Directory | [Uses]
1-Methyl-aminomethyl naphthalene has been used as reagent for the determination of isocyanates in air by UV or fluorescence detection. 1-Methyl-aminomethyl naphthalene has been used in the preparation of key intermediate required for the synthesis of terbinafine.
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