| Identification | More | [Name]
2-Phenylethylamine hydrochloride | [CAS]
156-28-5 | [Synonyms]
2-PHENYLETHYLAMINE HCL
2-PHENYLETHYLAMINE HYDROCHLORIDE
BETA-PHENYLETHYLAMINE HCL
BETA-PHENYLETHYLAMINE HYDROCHLORIDE
B-PHENYLETHYLAMINE HYDROCHLORIDE
PHENETHYLAMINE HYDROCHLORIDE
Phenethylammonium chloride
1-Phenyl-2-aminoethane hydrochloride
1-phenyl-2-aminoethanehydrochloride
Benzeneethanamine, hydrochloride
benzeneethanamine,hydrochloride
benzeneethanaminehydrochloride
beta-Phenethylamine hydrochloride
beta-phenethylaminehydrochloride
beta-Phenylathylaminhydrochlorid
USAF el-76
usafel-76
β-Phenylethylamine hydrochloride
B-PHENYLETHYLAMINE HCL
2-PhenylethylamineHydrochloride,99% | [EINECS(EC#)]
205-849-2 | [Molecular Formula]
C8H12ClN | [MDL Number]
MFCD00012893 | [Molecular Weight]
157.64 | [MOL File]
156-28-5.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [RTECS ]
SH7175000
| [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
eye-man 50 mg SEV AIMDAP 39,404,27 |
| Hazard Information | Back Directory | [Description]
2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes.1,2,3 This product is intended for forensic and research applications. | [Chemical Properties]
White to Light yellow powder to crystal. soluble in water, alcohol, ether. | [Uses]
CNS stimulant | [Preparation]
In a nitrogen environment, add the aliphatic nitro derivatives (0.6mmol), pinacol borane (3.6mmol, 6.0equiv), tetrahydrofuran (2mL), triethylboron (5mol%), and potassium tert-butoxide (5mol %) into a 10mL sealed tube and then place it in a 100 oil bath with heating and stirring for 24 hours. At the end of the reaction, add 2mL of 1M hydrochloric acid aqueous solution to the reaction solution and stir at room temperature for 6h. Finally, 2-Phenylethylamine hydrochloride is obtained by filtration.
 | [General Description]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com. | [Safety Profile]
Poison by skin contact, subcutaneous, and intravenous routes. A human eye irritant. A skin irritant and possible sensitizer. Human systemic effects by ingestion: blood pressure lowering, anorexia. When heated to decomposition it emits very toxic fumes of | [References]
[1] MASATO NAKAMURA Daiichiro N Akira Ishii. Characterization of β-phenylethylamine-induced monoamine release in rat nucleus accumbens: a microdialysis study[J]. European journal of pharmacology, 1998, 349 2: Pages 163-169. DOI: 10.1016/s0014-2999(98)00191-5
[2] H Y YANG N H N. Beta-phenylethylamine: a specific substrate for type B monoamine oxidase of brain.[J]. Journal of Pharmacology and Experimental Therapeutics, 1973, 187 2: 365-371.
[3] O. SUZUKI M. O Y Katsumata. Oxidation of β-Phenylethylamine by Both Types of Monoamine Oxidase: Examination of Enzymes in Brain and Liver Mitochondria of Eight Species[J]. Journal of Neurochemistry, 1981, 36 3: 1298-1301. DOI: 10.1111/j.1471-4159.1981.tb01734.x |
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