| Identification | Back Directory | [Name]
Azido-PEG8-t-butyl ester | [CAS]
1623791-99-0 | [Synonyms]
Azido-PEG8-Boc
Azido-PEG8-COOtBu
N3-PEG8-CH2CH2COOtBu
Azido-PEG8-tBu Ester
Azido-PEG8-t-butyl ester
Azido-PEG9-t-butly ester
N3-?PEG8-?t-?butyl ester
N3-PEG8-CH2CH2COOtBu,Azido-PEG8-t-butyl ester
4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-azido-, 1,1-dimethylethyl ester | [Molecular Formula]
C23H45N3O10 | [MDL Number]
MFCD22683291 | [MOL File]
1623791-99-0.mol | [Molecular Weight]
523.62 |
| Hazard Information | Back Directory | [Description]
Azido-PEG8-t-butyl ester is a click chemistry compound conpprising an azide group and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. | [Uses]
Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239. |
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