| Identification | Back Directory | [Name]
3-Aminopropyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate hydrochloride | [CAS]
1683535-53-6 | [Synonyms]
Apcin A HCL
3-Aminopropyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate hydrochloride | [Molecular Formula]
C10H15Cl4N5O2 | [MDL Number]
MFCD34167446 | [MOL File]
1683535-53-6.mol | [Molecular Weight]
379.06 |
| Hazard Information | Back Directory | [Uses]
Apcin-A monohydrochloride, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A monohydrochloride interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A monohydrochloride can be used to synthesize the PROTAC CP5V (HY-130257)[1]. | [References]
[1] Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2. DOI:10.1016/j.ebiom.2019.10.013 |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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