| Identification | Back Directory | [Name]
Bis-PEG1-PFP ester | [CAS]
1807539-02-1 | [Synonyms]
PFP-PEG1-PFP
Bis-PEG1-PFP ester
Propanoic acid, 3,3'-oxybis-, 1,1'-bis(2,3,4,5,6-pentafluorophenyl) ester | [Molecular Formula]
C18H8F10O5 | [MDL Number]
MFCD26127804 | [MOL File]
1807539-02-1.mol | [Molecular Weight]
494.24 |
| Hazard Information | Back Directory | [Description]
Bis-PEG1-PFP ester is a PEG linker with two PFP ester moieties. The PFP ester is amine-reactive, stable compound. PFP esters are less susceptible toward hydrolysis compared to NHS esters. The PEG linker increases the water solubility of compounds in aqueous environments. | [Uses]
Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Non-cleavable Linker | [References]
[1] CORTEZ, Alex, et al. ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST. WO2017072662A1. |
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