ChemicalBook--->CAS DataBase List--->18942-49-9

18942-49-9

18942-49-9 Structure

18942-49-9 Structure
IdentificationMore
[Name]

BOC-D-Phenylalanine
[CAS]

18942-49-9
[Synonyms]

BOC-D-PHE
BOC-D-PHENYLALANINE
BOC-D-PHE-OH
N-[-(1,1-DIMETHYLETHOXY)-CARBONYL]-D-PHENYLAMINE
N-ALPHA-T-BOC-D-PHENYLALANINE
N-ALPHA-T-BUTYLOXYCARBONYL-D-PHENYLALANINE
N-ALPHA-TERT-BUTYLOXYCARBONYL-D-PHENYLALANINE
N-BOC-D-PHENYLALANINE
N-T-BOC-D-PHENYLALANINE
N-(TERT-BUTOXYCARBONYL)-D-PHENYLALANINE
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID
RARECHEM AL BE 0806
T-BUTYLOXYCARBONYL-D-PHENYLALANINE
BOC-D-Phenylalanine, 99+%
N-[-(1,1-DIMETHYLETHOXY)-CARBONYL]-D-PHENYLALANINE
BOC-D-PHENYLALANINE-OH
[EINECS(EC#)]

606-177-6
[Molecular Formula]

C14H19NO4
[MDL Number]

MFCD00063149
[Molecular Weight]

265.3
[MOL File]

18942-49-9.mol
Chemical PropertiesBack Directory
[Appearance]

white fine crystalline powder
[Melting point ]

78-87 °C
[alpha ]

-26 º (c=2,ethanol)
[Boiling point ]

408.52°C (rough estimate)
[density ]

1.1356 (rough estimate)
[refractive index ]

-25 ° (C=1, EtOH)
[storage temp. ]

2-8°C
[solubility ]

DMSO, Ethanol, Methanol
[form ]

Fine Crystalline Powder
[pka]

3.88±0.10(Predicted)
[color ]

White
[Optical Rotation]

[α]20/D 25±1°, c = 1% in ethanol
[Water Solubility ]

insoluble
[BRN ]

3593396
[InChIKey]

ZYJPUMXJBDHSIF-LLVKDONJSA-N
[CAS DataBase Reference]

18942-49-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P304+P340
[Hazard Codes ]

Xi
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[HS Code ]

29242990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1,4-Dioxane-->L-Phenylalanine-->2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile-->N-Boc-D-Phenylalaninol-->Carbon tetrabromide-->D-Phenylalanine-->Benzoyl hydrazine-->Di-tert-butyl dicarbonate-->Benzyl bromide-->BOC-Glycine-->1,1'-Carbonyldiimidazole
[Preparation Products]

N-(tert-Butoxycarbonyl)-L-phenylalanine-->D-Phenylalanine methyl ester hydrochloride-->BOC-D-PHE-OSU-->N-Boc-D-phenylalanine N'-Methoxy-N'-MethylaMide
Questions and Answers (Q&A)Back Directory
[Description]

BOC-D-Phenylalanine is the BOC (tert-butyloxycarbonyl) protected form of D-phenylalanine. It can be used in the synthesis of benzo[de][1,7] napthyridinones as PARP1 inhibitors. It is also an important reagent during the manufacturing of proline-containing, ß-turn mimetic cycle tetrapeptides.
[References]

https://www.clearsynth.com/en/CST07663.html
http://www.biocompare.com/Protein-Biochemistry/10318-Boc-Protected-Phenylalanine-Monomers-and-Derivatives/
Hazard InformationBack Directory
[Chemical Properties]

white fine crystalline powder
[Uses]

Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrap eptides.
[Uses]

Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.
[reaction suitability]

reaction type: Boc solid-phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

BOC-D-Phenylalanine(18942-49-9)MS
BOC-D-Phenylalanine(18942-49-9)1HNMR
BOC-D-Phenylalanine(18942-49-9)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

BOC-D-Phenylalanine, 99+%(18942-49-9)
[Alfa Aesar]

N-Boc-D-phenylalanine, 98%(18942-49-9)
[Sigma Aldrich]

18942-49-9(sigmaaldrich)
[TCI AMERICA]

N-(tert-Butoxycarbonyl)-D-phenylalanine,>98.0%(T)(18942-49-9)
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