2194563-84-1

Directory

2194563-84-1 Structure

Identification	Back Directory
[Name] Methyltetrazine-PEG4-NH-Boc
[CAS] 2194563-84-1
[Synonyms] Methyltetrazine-PEG4-NH-Boc tert-Butyl (2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate
[Molecular Formula] C22H33N5O6
[MDL Number] MFCD31615440
[MOL File] 2194563-84-1.mol
[Molecular Weight] 463.53

Chemical Properties	Back Directory
[density ] 1.166±0.06 g/cm3(Predicted)
[solubility ] Soluble in DMSO, DCM, DMF
[pka] 12.22±0.46(Predicted)

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H319-H335
[Precautionary statements ] P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Hazard Information	Back Directory
[Description] Methyltetrazine-PEG4-NH-Boc is a click chemistry reagent attached with a Boc protecting group. The hydrophilic PEG spacer arm improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The Boc protecting group can be removed under acidic conditions.
[Uses] Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2194563-84-1 suppliers list

Company Name:	Wuhan Topule Biopharmaceutical Co., Ltd
Tel:	+8618327326525 , +8618327326525
Website:	topule.com/

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	+undefined18143011203 , +undefined18143011203
Website:	www.chemextension.com/

Company Name:	ComMedX (Computational Medicine Beijing Co., Ltd.)
Tel:	+86-18519000250 +86-18519000250 , +86-18519000250
Website:	www.commedx.com/en/

Company Name:	Shanghai EFE Biological Technology Co., Ltd.
Tel:	021-65675885 18964387627
Website:	http://www.efebio.com

Company Name:	Henan's chemical products co., LTD
Tel:	0371-60919097 15378766539
Website:	http://www.psaichem.cn/

Company Name:	Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel:	029-86217788 13892832556
Website:	http://www.xinyanbm.com/

Company Name:	Henan Weitesi Chemical Technology Co. LTD
Tel:	0371-0371-55135753 18003832934
Website:	https://www.chemicalbook.com/supplier/23629017/

Company Name:	Nanjing Shizhou Biology Technology Co.,Ltd
Tel:	025-85563444 18351873721
Website:	http://www.synzest.com

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 15801484223;
Website:	http://www.jm-bio.com/

Company Name:	Wuhan Augda Biotechnology Co., Ltd
Tel:	15071299552
Website:	https://www.chemicalbook.com/supplier/24275232/1.htm

Company Name:	Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel:	0431-80514535 19917294565
Website:	www.chemextension.com

Tags:2194563-84-1 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login