2241669-88-3

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2241669-88-3 Structure

Identification	Back Directory
[Name] E3 ligase Ligand 18
[CAS] 2241669-88-3
[Synonyms] E3 ligase Ligand 18 L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]-
[Molecular Formula] C17H17ClN6O4S
[MDL Number] MFCD32263215
[MOL File] 2241669-88-3.mol
[Molecular Weight] 436.87

Hazard Information	Back Directory
[Uses] E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[IC 50] Cereblon
[References] [1] Heterocyclic compound. WO2018143403A1.

Spectrum Detail	Back Directory
[Spectrum Detail] E3 ligase Ligand 18(2241669-88-3)¹HNMR

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