| Identification | Back Directory | [Name]
PC SPDP-NHS carbonate ester | [CAS]
2279944-61-3 | [Synonyms]
PC SPDP-NHS carbonate ester | [Molecular Formula]
C25H28N4O10S2 | [MDL Number]
MFCD31811480 | [MOL File]
2279944-61-3.mol | [Molecular Weight]
608.64 |
| Chemical Properties | Back Directory | [density ]
1.46±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid | [pka]
15.26±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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