ChemicalBook--->CAS DataBase List--->2341841-02-7

2341841-02-7

Request For Quotation
2341841-02-7 Structure

2341841-02-7 Structure
IdentificationBack Directory
[Name]

Thalidomide-linker 10
[CAS]

2341841-02-7
[Synonyms]

Thalidomide-linker 10
Thalidomide-O-amido-C2-NH2
-oxyacetamide-alkylC2-amine
Thalidomide-O-amido-C2-NH2 hydrochloride
Thalidomide 4'-oxyacetamide-alkyl-C2-amine (hydrochloride)
N-(2-aminoethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
[Molecular Formula]

C17H19ClN4O6
[MDL Number]

MFCD32705133
[MOL File]

2341841-02-7.mol
[Molecular Weight]

410.81
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
[IC 50]

Cereblon
[storage]

Store at -20°C
[References]

[1] Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952. DOI:10.1016/j.ejmech.2019.111952
Spectrum DetailBack Directory
[Spectrum Detail]

Thalidomide-linker 10(2341841-02-7)1HNMR
2341841-02-7 suppliers list
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 18916372613
Website: www.shyuanye.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Telephone: QQ：65489617 13301690235
Website: www.atkchemical.com/
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Telephone: +86-156-80926068 +86-15680926068
Website: http://www.confluore.cn/
Company Name: SuZhou Medinoah Co.,LTD.  
Telephone: 0512-69561983 13914027025
Website: http://www.medinoah.com/
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Telephone: 400-9205774 400-920-5774
Website: www.glpbio.cn
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Telephone: 13504435624
Website: https://www.wodapro.com
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Telephone: 400-8210725 4008210725
Website: https://www.leyan.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Abosyn  
Telephone: 0512-69561983 13914027025
Website: abosyn.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.  
Telephone: 025-025-66113011 15955137747
Website: http://www.aikonchem.com
Company Name: Accela ChemBio Co.,Ltd.  
Telephone: 4000665055
Website: www.shao-yuan.com
Company Name: Shanghai Aladdin Biochemical Technology Co.,Ltd.  
Telephone: 6206333 13167063860
Website: www.aladdin-e.com/
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
Telephone: 18143011203
Website: http://www.chemextension.com/
Company Name: Shandong Dayou Pharmaceutical Research and Development Co., Ltd.  
Telephone: dayouchem@126.com 15165037910
Website:
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Telephone: 17634413542
Website: mengtaichem.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Telephone: 13370042665 18916960931
Website: www.amole.com.cn/
Tags:2341841-02-7 Related Product Information
1950635-15-0 2204226-02-6 175724-30-8 2411681-87-1 2415263-07-7 2245697-84-9 2245697-86-1 2496687-00-2 2098799-77-8 1799711-24-2 1957236-20-2 1061605-21-7 1957235-94-7 441049-84-9