| Identification | Back Directory | [Name]
Thalidomide-linker 13 | [CAS]
2204226-02-6 | [Synonyms]
Thalidomide-linker 13
-oxyacetamide-PEG1-amine
Thalidomide-O-amido-PEG1-NH2 hydrochloride
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
N-(2-(2-Aminoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride | [Molecular Formula]
C19H23ClN4O7 | [MDL Number]
MFCD32063469 | [MOL File]
2204226-02-6.mol | [Molecular Weight]
454.86 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. | [IC 50]
Cereblon | [storage]
Store at -20°C | [References]
[1] Chessum NEA, et al. Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). J Med Chem. 2018 Feb 8;61(3):918-933. DOI:10.1021/acs.jmedchem.7b01406 |
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