2245697-84-9

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2245697-84-9 Structure

Identification	Back Directory
[Name] Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
[CAS] 2245697-84-9
[Synonyms] -ether-PEG3-amine Thalidomide 4&rsquo -oxyacetamide-PEG3-amine -oxyacetamide-alkylC8-amine Thalidomide-O-amido-PEG3-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
[Molecular Formula] C23H31ClN4O9
[MDL Number] MFCD31656717
[MOL File] 2245697-84-9.mol
[Molecular Weight] 542.97

Chemical Properties	Back Directory
[storage temp. ] Store at -20°C
[solubility ] Soluble in DMSO
[form ] Solid
[color ] Off-white to yellow

Hazard Information	Back Directory
[Uses] Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].
[IC 50] Cereblon
[storage] Store at -20°C
[References] [1] Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.

Spectrum Detail	Back Directory
[Spectrum Detail] Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride(2245697-84-9)¹HNMR

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