| Identification | Back Directory | [Name]
(S,R,S)-AHPC-C6-NH2 hydrochloride | [CAS]
2360522-76-3 | [Synonyms]
(S,R,S)-AHPC-C6-NH2 HCl salt
(2S,4R)-1-((S)-2-(7-aminoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | [Molecular Formula]
C29H44ClN5O4S | [MOL File]
2360522-76-3.mol | [Molecular Weight]
594.21 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1]. | [IC 50]
VHL | [References]
[1] Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1. |
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|