| Identification | Back Directory | [Name]
E3 Ligase Ligand-Linker Conjugates 56 | [CAS]
2375564-62-6 | [Synonyms]
VHL Ligand-Linker Conjugates 15
E3 Ligase Ligand-Linker Conjugates 56 | [Molecular Formula]
C37H45FN4O8S | [MDL Number]
MFCD32201090 | [MOL File]
2375564-62-6.mol | [Molecular Weight]
724.84 |
| Hazard Information | Back Directory | [Uses]
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs[1]. | [IC 50]
VHL | [References]
[1] Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. DOI:10.1038/s41589-019-0294-6 |
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