| Identification | Back Directory | [Name]
Thalidomide-linker 9 | [CAS]
2376990-29-1 | [Synonyms]
-ether-alkylC4-amine
Thalidomide-linker 9
Pomalidomide-O-C4-NH2
Thalidomide-O-C4-NH2 hydrochloride
4-(4-Aminobutoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
4-(4-aminobutoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | [Molecular Formula]
C17H20ClN3O5 | [MDL Number]
MFCD32705123 | [MOL File]
2376990-29-1.mol | [Molecular Weight]
381.81 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide (HY-14658) based cereblon ligand and a linker used in PROTAC technology. | [IC 50]
Cereblon | [storage]
Store at -20°C | [References]
[1] Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.??[Content Brief] DOI:10.1038/nature13527 |
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| Company Name: |
Henan Alfachem Co.,Ltd.
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| Tel: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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