| Identification | Back Directory | [Name]
CVM-05-002 | [CAS]
2428738-43-4 | [Synonyms]
CVM-05-002
N-[4-[5-[(Z)-(2-Amino-4-oxo-5(4H)-thiazolylidene)methyl]-3-pyridinyl]phenyl]methanesulfonamide | [Molecular Formula]
C16H14N4O3S2 | [MOL File]
2428738-43-4.mol | [Molecular Weight]
374.44 |
| Hazard Information | Back Directory | [Uses]
CVM-05-002 is a PI5P4K inhibitor, with IC50 values of 0.27 μM and 1.7 μM for PI5P4Kα and PI5P4Kβ, respectively[1]. | [References]
[1] Theresa D Manz, et al. Discovery and Structure-Activity Relationship Study of ( Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. J Med Chem. 2020 May 14;63(9):4880-4895. DOI:10.1021/acs.jmedchem.0c00227 |
|
|