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2471969-07-8

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2471969-07-8 Structure

2471969-07-8 Structure
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[Name]

PI5P4Ks-IN-3
[CAS]

2471969-07-8
[Synonyms]

PI5P4Ks-IN-3
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[Uses]

PI5P4Ks-IN-3 (compound 30) is a covalent inhibitor of PI5P4K with IC50s of 1.34 μM (PI5P4Kα)，and 9.9 μM (PI5P4Kβ)，respectively. PI5P4Ks-IN-3 shows weak cellular activity[1].
[References]

[1] Manz TD, et al. Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Med Chem Lett. 2019 Nov 3;11(3):346-352. DOI:10.1021/acsmedchemlett.9b00402
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