| Chemical Properties | Back Directory | [Boiling point ]
505.0±50.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.89±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells[1]. | [IC 50]
EBOV; MARV | [References]
[1] Gaisina IN, et, al. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225. DOI:10.1021/acs.jmedchem.0c00463 |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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