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2624336-87-2

2624336-87-2 Structure

2624336-87-2 Structure
IdentificationBack Directory
[Name]

Lenalidomide 4'-PEG3-amine dihydrochloride
[CAS]

2624336-87-2
[Synonyms]

Lenalidomide 4'-PEG3-amine
Lenalidomide4'-PEG3-aminedihydrochloride
Lenalidomide 4'-PEG3-amine dihydrochloride
Hazard InformationBack Directory
[Uses]

Lenalidomide 4'-PEG3-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG3-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
[References]

[1] Wang S, et al. Monofunctional intermediates for ligand-dependent target protein degradation. China, WO2017176958A1. 2017-10-12.
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