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IdentificationBack Directory
[Name]

CK156
[CAS]

NoCAS
[Synonyms]

CK156
[Molecular Formula]

C21H25N5O3
[MOL File]

2910938-59-7.mol
[Molecular Weight]

395.46
Chemical PropertiesBack Directory
[Boiling point ]

591.717±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.322±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

Solid
[pka]

14.774±0.20(predicted)
[color ]

White to light yellow
[InChI]

1S/C21H25N5O3/c1-21(2,3)25-20(27)15-5-4-14-12-17(15)29-11-10-28-9-7-22-18-6-8-26-19(24-18)16(14)13-23-26/h4-6,8,12-13H,7,9-11H2,1-3H3,(H,22,24)(H,25,27)
[InChIKey]

YCFFONJEHNSECY-UHFFFAOYSA-N
[SMILES]

CC(C)(C)NC(C(C=C1)=C(OCCOCCNC2=N3)C=C1C4=C3N(C=C2)N=C4)=O
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Biological Activity]

CK156 is a potent and selective DRAK1 inhibitor (IC50 = 49 nM by cell-free radiometric assayIC50 = 181 nM by cellular NanoBRETKD = 21 nM by ITCselectivity by a 468-kinase panel) with good selectivity over DRAK2 (61% inhibition at 1 μMIC50 = 8 μM by NanoBRET).
2910938-59-7 suppliers list
Company Name: Merck KGaA  
Tel: 21-20338288
Website: www.sigmaaldrich.cn
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Website: www.targetmol.cn/
Tags: Related Product Information
1638644-62-8 2387510-88-3 2910938-59-7