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2913152-30-2

2913152-30-2 Structure

2913152-30-2 Structure
IdentificationBack Directory
[Name]

STING Agonist 12L
[CAS]

2913152-30-2
[Synonyms]

STING Agonist 12L
[Molecular Formula]

C18H10FN5O3
[MOL File]

2913152-30-2.mol
[Molecular Weight]

363.3
Chemical PropertiesBack Directory
[Boiling point ]

604.710±55.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.554±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[solubility ]

DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 5 mg/mlPBS (pH 7.2): 2 mg/ml
[pka]

2.597±0.36(predicted)
Hazard InformationBack Directory
[Uses]

STING agonist-34 (Compound 12L) is a potent STING agonist with an IC50 value of 1.15 μM and an EC50 of 0.38 μM in THP1 cells. STING agonist-34 could be used in cancer research[1].
[References]

[1] Li R, et al. Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein. J Chem Inf Model. 2023 Oct 13. DOI:10.1021/acs.jcim.3c00984
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