| Identification | Back Directory | [Name]
2H-1-Benzopyran-2-one, 3-[2-[(3-acetylphenyl)amino]-4-thiazolyl]- | [CAS]
317328-17-9 | [Synonyms]
ZINC00784494
2H-1-Benzopyran-2-one, 3-[2-[(3-acetylphenyl)amino]-4-thiazolyl]- | [Molecular Formula]
C20H14N2O3S | [MOL File]
317328-17-9.mol | [Molecular Weight]
362.4 |
| Chemical Properties | Back Directory | [Boiling point ]
605.2±65.0 °C(Predicted) | [density ]
1.396±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
2.66±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1]. | [References]
[1] Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22(16):8581. DOI:10.3390/ijms22168581 |
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