| Identification | Back Directory | [Name]
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N-(tetrahydro-2H-pyran-4-yl)- | [CAS]
1995025-05-2 | [Synonyms]
ZINC194100678
N-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N-(tetrahydro-2H-pyran-4-yl)- | [Molecular Formula]
C10H13N5O | [MOL File]
1995025-05-2.mol | [Molecular Weight]
219.24 |
| Hazard Information | Back Directory | [Uses]
ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1]. | [IC 50]
PAK1: 8.37 μM (IC50) | [References]
[1] Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220. DOI:10.1016/j.ejmech.2020.112220 |
|
|