ChemicalBook--->CAS DataBase List--->423763-19-3

423763-19-3

423763-19-3 Structure

423763-19-3 Structure
IdentificationBack Directory
[Name]

HEPTAETHYLENE GLYCOL Monobenzyl ether
[CAS]

423763-19-3
[Synonyms]

BnO-PEG7-OH
CAS_423763-19-3
HO-(CH2CH2O)7-Bn
Benzyl-PEG8-alcohol
Benzyl-PEG7-alcohol
HEPTAETHYLENE GLYCOL Monobenzyl ether
1-phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-ol
2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, 1-phenyl-
Heptaethylene glycol monobenzyl ether, BnO-PEG7-OH
2-[2-[2-[2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
[Molecular Formula]

C21H36O8
[MDL Number]

MFCD24682795
[MOL File]

423763-19-3.mol
[Molecular Weight]

416.506
Chemical PropertiesBack Directory
[Boiling point ]

508.4±45.0 °C(Predicted)
[density ]

1.099±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

Liquid
[pka]

14.36±0.10(Predicted)
[color ]

Colorless to light yellow
[InChI]

InChI=1S/C21H36O8/c22-6-7-23-8-9-24-10-11-25-12-13-26-14-15-27-16-17-28-18-19-29-20-21-4-2-1-3-5-21/h1-5,22H,6-20H2
[InChIKey]

ZCSFSTZVHMIOOJ-UHFFFAOYSA-N
[SMILES]

C(C1=CC=CC=C1)OCCOCCOCCOCCOCCOCCOCCO
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

Benzyl-PEG8-alcohol is a PEG linker including a benzyl protecting group, which can be deprotected under catalytic hydrogenation and reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG8 units bolster the aqueous media solubility of the compound. Please contact us for GMP-grade inquiries.
[Uses]

Benzyl-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

HEPTAETHYLENE GLYCOL Monobenzyl ether(423763-19-3)1HNMR
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