| Identification | Back Directory | [Name]
2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL | [CAS]
86259-87-2 | [Synonyms]
86259-87-2 BnO-PEG4-OH CAS_86259-87-2 Benzyl-PEG4-OH Benzyl-PEG5-alcohol Benzyl-PEG4-alcohol TETRAETHYLENE GLYCOL MONOBENZYL ETHER 13-Phenyl-3,6,9,12-tetraoxatridecan-1-ol 1-Phenyl-2,5,8,11-tetraoxatridecan-13-ol 3,6,9,12-Tetraoxatridecan-1-ol, 13-phenyl- 2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL | [Molecular Formula]
C15H24O5 | [MDL Number]
MFCD06797175 | [MOL File]
86259-87-2.mol | [Molecular Weight]
284.35 |
| Chemical Properties | Back Directory | [Boiling point ]
170-174 °C(Press: 25 Torr) | [density ]
1.10 | [refractive index ]
1.4980 to 1.5020 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Sparingly), DMSO (Sparingly) | [form ]
Oil | [pka]
14.36±0.10(Predicted) | [color ]
Pale Yellow to Light Yellow | [InChI]
InChI=1S/C15H24O5/c16-6-7-17-8-9-18-10-11-19-12-13-20-14-15-4-2-1-3-5-15/h1-5,16H,6-14H2 | [InChIKey]
QDPIVUQXPXUNLN-UHFFFAOYSA-N | [SMILES]
C(O)COCCOCCOCCOCC1=CC=CC=C1 | [CAS DataBase Reference]
86259-87-2 |
| Hazard Information | Back Directory | [Description]
Benzyl-PEG5-alcohol is a PEG linker with a acid labile, benzyl group and a reactive primary alcohol. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs | [References]
[1] Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1. |
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