| Identification | Back Directory | [Name]
(2-pyridyldithio)-PEG4 acid | [CAS]
581065-93-2 | [Synonyms]
(2-pyridyldithio)-PEG4 acid | [Molecular Formula]
C16H25NO6S2 | [MDL Number]
MFCD32641907 | [MOL File]
581065-93-2.mol | [Molecular Weight]
391.5 |
| Chemical Properties | Back Directory | [Boiling point ]
546.4±50.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [form ]
Viscous Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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