| Identification | More | [Name]
2,3-Dimethoxy-5-methyl-p-benzoquinone | [CAS]
605-94-7 | [Synonyms]
2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE
2,3-dimethoxy-5-methyl-2,5-cyclohexadiene-1,4-dione
2,3-DIMETHOXY-5-METHYLBENZOQUINONE
2,3-DIMETHOXY-5-METHYL-P-BENZOQUINONE
2,3-DIMETHOXYL-5-METHYL-1,4-BENZOQUINONE
2,3-DIMETHOXYMETHYLBENZOQUINONE
2,5-CYCLOHEXADIENE-1,4-DIONE, 2,3-DIMETHOXY-5-METHYL-
COENZYME Q
COENZYME Q0
COENZYME Q10
COENZYME QO
DIMETHOXY-5-METHYLBENZOQUINONE, 2,3-
2,3-Dimethoxy-5-methylbenzo-1,4-quinone
2-Methyl-5,6-dimethoxybenzoquinone
Coq0
p-Benzoquinone, 2,3-dimethoxy-5-methyl-
q0
Ubiquinone 0
Ubiquinone q0
2,3-dimethyoxyl-5-methyl-1,4-benzoquinone(coenzyme Q0) | [EINECS(EC#)]
210-100-8 | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00001595 | [Molecular Weight]
182.17 | [MOL File]
605-94-7.mol |
| Chemical Properties | Back Directory | [Appearance]
red or orange crystals or fibres | [Melting point ]
58-60 °C(lit.) | [Boiling point ]
331.4±42.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): 0.2 mg/ml | [Water Solubility ]
almost transparency in hot Water | [form ]
Crystalline Powder or Needles | [color ]
Red to orange | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents. | [Sensitive ]
Light Sensitive | [BRN ]
1640422 | [InChI]
1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3 | [InChIKey]
UIXPTCZPFCVOQF-UHFFFAOYSA-N | [SMILES]
COC1=C(OC)C(=O)C(C)=CC1=O | [CAS DataBase Reference]
605-94-7(CAS DataBase Reference) | [NIST Chemistry Reference]
2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-(605-94-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [F ]
8-10-21 | [HS Code ]
29146990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Benzoic acid, 2-hydroxy-3,4,5-trimethoxy--->4,5-Dimethoxy-3-hydroxytoluene-->2,3,4-Trimethoxyphenol-->2-methoxy-5-methyl-1,4-benzoquinone-->2,3,4-Trimethoxy-6-methylphenol-->2,3,4,5-Tetramethoxytoluene-->Methyl 3,4,5-trimethoxybenzoate-->3,4-Dimethoxytoluene-->3,4,5-Trimethoxytoluene-->2,3,4-Trimethoxybenzaldehyde-->3,4,5-Trimethoxy benzoic acid | [Preparation Products]
Coenzyme Q10-->2,3-Dimethoxy-5-methyl-1,4-hydroquinone |
| Hazard Information | Back Directory | [Chemical Properties]
red or orange crystals or fibres | [Uses]
2,3-Dimethoxy-5-methyl-p-benzoquinone (Ubidecarenone EP Impurity A) | [Definition]
ChEBI: A derivative of benzoquinone carrying a 5-methyl substituent; and methoxy substituents at positions 2 and 3. The core structure of the ubiquinone group of compounds. | [Synthesis Reference(s)]
Chemical and Pharmaceutical Bulletin, 16, p. 2343, 1968 DOI: 10.1248/cpb.16.2343
The Journal of Organic Chemistry, 53, p. 5453, 1988 DOI: 10.1021/jo00258a010 | [General Description]
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells. | [Biochem/physiol Actions]
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure. | [Purification Methods]
It crystallises in red needles from pet ether (b 40-60o) and sublimes at high vacuum at a bath temperature of 46-48o [Ashley et al. J Chem Soc 441 1938, UV in EtOH: Vischer J Chem Soc 815 1953, UV in cyclohexane: Morton et al. Helv Chim Acta 41 2343 1858, Aghoramurthy et al. Chem Ind (London) 1327 1954]. [Beilstein 8 IV 2721.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|