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663598-61-6

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663598-61-6 Structure

663598-61-6 Structure
IdentificationBack Directory
[Name]

2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate
[CAS]

663598-61-6
[Synonyms]

NO2-SPP
2,5-Dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate
[Molecular Formula]

C14H15N3O6S2
[MDL Number]

MFCD20230055
[MOL File]

663598-61-6.mol
[Molecular Weight]

385.42
Chemical PropertiesBack Directory
[Boiling point ]

548.7±60.0 °C(Predicted)
[density ]

1.51±0.1 g/cm3(Predicted)
[pka]

-2.22±0.29(Predicted)
Hazard InformationBack Directory
[Uses]

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Qiming Chen, et al. Anti-integrin immunoconjugates, methods and uses. WO2006062779A2.
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