| Identification | Back Directory | [Name]
Benzyl-PEG5-Azide | [CAS]
86770-72-1 | [Synonyms]
CAS_86770-72-1
Benzyl-PEG4-N3
Benzyl-PEG5-N3
Benzyl-PEG4-azide
BrCH2CONH-PEG2-N3
Benzyl-PEG5-Azide
Bromoacetamido-PEG2-Azide
17-azido-1-phenyl-2,5,8,11,14-pentaoxaheptadecane | [Molecular Formula]
C17H27N3O5 | [MDL Number]
MFCD28976657 | [MOL File]
86770-72-1.mol | [Molecular Weight]
353.413 |
| Hazard Information | Back Directory | [Description]
Bromoacetamido-PEG2-azide is a heterobifunctional PEG linker containing a reactive bromoacetamido and a terminal azide.The bromoacetamidogroup is a very reactive group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. | [Uses]
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Henan Alfachem Co.,Ltd.
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0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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Nextpeptide Inc
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http://www.nextpeptide.com/ |
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