| Identification | More | [Name]
5-Norbornene-2-carbonitrile | [CAS]
95-11-4 | [Synonyms]
5-NORBORNENE-2-CARBONITRILE
BICYCLO[2.2.1]-5-HEPTENE-2-CARBONITRILE
BICYCLO[2.2.1]HEPT-5-ENE-2-CARBONITRILE
TIMTEC-BB SBB007934
5-Cyanobicyclo[2.2.1]hept-2-ene
5-NORBORNENE-2-CARBONITRILE, 98%, MIXTUR E OF ISOMERS
5-norbornene-2-carbonitrile, mixture of isomers
2-Cyano-5-norbornene
2-Cyanobicyclo[2.2.1]hept-5-ene
5-Cyano-2-norbornene
Bicyclo[2.2.1]-5-hepten-2-carbonitrile
5-Norbornene-2-carbonitrile, 98%, mixture of endo and exo
5-Norbornene-2-carbonitrile, mixture of endo and exo
2-Cyanonorborn-5-ene
Bicyclo[2.2.1]hept-2-ene-5-carbonitrile
Norborn-5-ene-2-carbonitrile | [EINECS(EC#)]
202-391-5 | [Molecular Formula]
C8H9N | [MDL Number]
MFCD00167563 | [Molecular Weight]
119.16 | [MOL File]
95-11-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3
| [RTECS ]
RB7930000
| [HS Code ]
29269090 | [Toxicity]
LD50 ivn-mus: 10 mg/kg CSLNX* NX#00780 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colourless liquid | [Uses]
Bicyclo[2.2.1]hept-2-ene-5-carbonitrile is used in method for continuously preparing cyanonorbornene by using microchannel reactor. | [General Description]
The hydrogenation of 5-norbornene-2-carbonitrile was studied using real-time mass spectrometric analysis. | [Safety Profile]
A poison by intravenous route.When heated to decomposition it emits toxic vapors ofNOx. | [Synthesis]
The general procedure for the synthesis of 3,7-dimethylocta-1,6-diene and bicyclo[2.2.1]hept-5-ene-2-carbonitrile from the compound (CAS:67403-76-3) and dicycloheptadiene was as follows: to a 4 mL screw-capped vial in an argon-protected glove box were added sequentially the compound 69 (82.6 mg, 0.50 mmol), norepiglottidiene 8 (51 μL, 0.5 mmol), hexane solution of 1.0 M AIMe2Cl (50 μL, 10.0 mol%, 0.05 mmol), Ni(COD)2 (3.45 mg, 2.5 mol%, 12.5 μmol), and DPEphos (6.75 mg, 2.5 mol%, 12.5 μmol) in THF ( 1.0 mL) solution. The vials were removed from the glove box and the reaction temperature was controlled at 28°C. The reaction mixture was stirred at 28 °C for 16 h and then concentrated under reduced pressure. The residue was purified by silica gel fast column chromatography (100% pentane as eluent) to afford product 70 (49.0 mg, 71% yield). The structure of the product was confirmed by 1H NMR (500 MHz, CDCl3) and 13C NMR (125 MHz, CDCl3) as follows: 1H NMR δ 5.74-5.64 (m, 1H), 5.13-5.06 (m, 1H), 4.99-4.88 (m, 2H), 2.12 (p, J=7.0 Hz, 1H ), 2.01-1.89 (m, 2H), 1.68 (s, 3H), 1.60 (s, 3H), 1.35-1.26 (m, 2H), 0.99 (d, J=6.9Hz, 3H); 13C NMR δ 144.91, 131.44, 124.80, 112.61, 37.51, 36.89, 25.88, 20.30, 17.83. | [References]
[1] Patent: WO2017/93149, 2017, A1. Location in patent: Page/Page column 28 |
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