gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1)
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- CAS-Nr.
- 980-71-2
- Bezeichnung:
- gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1)
- Englisch Name:
- Brompheniramine hydrogen maleate
- Synonyma:
- BROMPHENIRAMINE MALEATE;dimegan;dimetane;dimotane;ilvinmaleate;Rolabromophen;dimetanemaleate;Brompheniramine MaL;BroMpheniraMine hydr;parabromdylaminemaleate
- CBNumber:
- CB2736194
- Summenformel:
- C20H23BrN2O4
- Molgewicht:
- 435.31
- MOL-Datei:
- 980-71-2.mol
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gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1) Eigenschaften
- Schmelzpunkt:
- 134-135°C
- Flammpunkt:
- 9℃
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- Soluble in water, freely soluble in ethanol (96 per cent), in methanol and in methylene chloride.
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- maximale Wellenlänge (λmax)
- 261nm(lit.)
- Merck
- 14,1443
- Stabilität:
- Hygroscopic
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
- InChIKey
- SRGKFVAASLQVBO-BTJKTKAUSA-N
- SMILES
- C(C1=CC=C(Br)C=C1)(C1=NC=CC=C1)CCN(C)C.C(O)(=O)/C=C\C(O)=O
- LogP
- 3.565 (est)
- CAS Datenbank
- 980-71-2(CAS DataBase Reference)
- EPA chemische Informationen
- 2-Pyridinepropanamine, .gamma.-(4-bromophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1) (980-71-2)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn,Xi,T,F |
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| R-Sätze: |
22-39/23/24/25-23/24/25-11 |
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| S-Sätze: |
36-45-36/37-16-7 |
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| RIDADR |
3249 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
US4025000 |
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| TSCA |
TSCA listed |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
38220090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1) Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Brompheniramine is a first generation antihistamine of the propylamine class. It antagonizes histamine H
1 receptors (K
i = 6.06 nM) and also inhibits the reuptake of serotonin and norepinephrine.
Chemische Eigenschaften
White Solid
Verwenden
Antihistaminic;H1 Antagonist
Definition
ChEBI: The maleic acid salt of brompheniramine. A histamine H1 receptor antagonist, it is used for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Allgemeine Beschreibung
Brompheniraminemaleate, (+)2-[p-bromo-α-[2-(dimethylamino)ethyl]benzyl]pyridine bimaleate (Dimetane), differs fromchlorpheniramine by the substitution of a bromine atom forthe chlorine atom. Its actions and uses are like those of chlorpheniramine.It has a half-life of 25 hours, which is almosttwice that of chlorpheniramine.
Nebenwirkungen
The side effects of this
medication are similar to other classes of sedative antihistamines. Some medications
include parabens. Patients sensitive to parabens may develop a sensitivity
reaction.
gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 293)Lieferanten
980-71-2(gamma-(4-Bromphenyl)-N,N-dimethyl-2-pyridin-propanamin, (Z)-2-butendioat (1:1))Verwandte Suche:
- 2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate(1:1)
- 2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)-pyridinmaleate(1:1)
- dimegan
- dimetane
- dimetanemaleate
- RS-brompheniramine maleate
- dimotane
- g-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanaminemaleate
- gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(z)-2-butenedioate
- gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(z)-butenedioate
- ilvinmaleate
- parabromdylaminemaleate
- parabromodylaminemaleate
- γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanaminemaleate
- 1-(n,n-dimethylamino)-3-(p-bromophenyl)-3-(alpha-pyridyl)propane maleate
- 1-p-bromophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate
- BROMOPHENIRAMINE MALEATE
- (+/-)-BROMPHENIRAMINE MALEATE SALT
- BROMPHENIRAMINE MALEATE SALT
- brompheniramine hydrogen maleate
- BROMPHENIRAMINEMALEATE,USP
- BROMPHENIRAMINE MALEATE, PHARMA
- Bromopheniramine Maleate Salt
- Brompheniramine Maleate (125 mg)
- BroMpheniraMine hydr
- γ-(4-BroMophenyl)-N,N-diMethyl-
- γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine,(2Z)-2-butenedioate (1:1)
- Brompheniramine maleate solution
- Brompheniramine maleate CRS
- Rolabromophen
- Brompheniramine MaL
- 3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate
- Brompheniramine hydrogen maleate USP/EP/BP
- Brompheniramine maleateQ: What is
Brompheniramine maleate Q: What is the CAS Number of
Brompheniramine maleate Q: What is the storage condition of
Brompheniramine maleate Q: What are the applications of
Brompheniramine maleate
- TIANFU-CHEM 980-71-2 Brompheniramine hydrogen maleate
- Brompheniramine Maleate (1078008)
- β-Phenyl-γ-aminobutyric acid
- Brompheniramine maleate in methanol
- Brompheniramine maleate 100 μg/ml Methanol
- C10781600 (±)-BrompheniraminEmaleate
- Brompheniramine maleate, 10 mM in DMSO
- (±)-Brompheniramine maleate salt
- Brompheniramine Maleate 1.0 mg/ml in Methanol (as free base)
- (±)-Brompheniramine maleate
- Brompheniramine maleate (Standard)
- BROMPHENIRAMINE MALEATE
- 980-71-2
- 80-71-2
- C4H4O4C16H19BrN2
- C20H23BrN204
- C20H23BrN2O4
- C16H19BrN2C4H4O4C20H23BrN2O4
- C16H19BrN2C4H4O4
- C16H19BrN2C4H4O4C20H
- C16H19BrN2C4H4
- Amines
- Aromatics
- Heterocycles
