ChemicalBook >> CAS DataBase List >>INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER

CAS No.
338760-26-2
Chemical Name:
INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER
Synonyms
METHYL 1-BOC-1H-INDOLE-3-CARBOXYLATE;tert-butyl methyl 1H-indole-1,3-dicarboxylate;1-tert-Butyl 3-Methyl 1H-indole-1,3-dicarboxylate;methyl 1-tert-butoxycarbonyl-1H-indole-3-carboxylate;INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER;1H-Indole-1,3-dicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester
CBNumber:
CB0103868
Molecular Formula:
C15H17NO4
Molecular Weight:
275.3
MDL Number:
MFCD06658476
MOL File:
338760-26-2.mol
MSDS File:
SDS
Last updated:2026-05-27 17:22:48
Product description Number Pack Size Price
1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate FB139922 500mg $250
1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate FB139922 250mg $250
1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate FB139922 1000mg $400
1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate FB139922 2000mg $680
1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate FB139922 5000mg $1350

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER Properties

Melting point 127.0 °C
Boiling point 387.3±34.0 °C(Predicted)
Density 1.16±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FB139922 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate 338760-26-2 500mg $250 2026-06-04 Buy
Biosynth FB139922 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate 338760-26-2 250mg $250 2026-06-04 Buy
Biosynth FB139922 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate 338760-26-2 1000mg $400 2026-06-04 Buy
Biosynth FB139922 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate 338760-26-2 2000mg $680 2026-06-04 Buy
Biosynth FB139922 1-tert-Butyl 3-methyl 1H-indole-1,3-dicarboxylate 338760-26-2 5000mg $1350 2026-06-04 Buy
Product number Packaging Price Buy
FB139922 500mg $250 Buy
FB139922 250mg $250 Buy
FB139922 1000mg $400 Buy
FB139922 2000mg $680 Buy
FB139922 5000mg $1350 Buy

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER Chemical Properties,Uses,Production

Synthesis

Methyl indole-3-carboxylate

942-24-5

Di-tert-butyl dicarbonate

24424-99-5

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER

338760-26-2

Methyl indole-3-carboxylate (17.1 mmol) was placed in a 50 mL round-bottomed flask, NaH (1.5 eq.) was added and cooled under ice bath conditions. THF (20 mL) was added slowly and stirred for 30 minutes. Subsequently, di-tert-butyl dicarbonate (1.5 eq.) was added and the reaction continued to stir overnight. Upon completion of the reaction, the reaction was quenched with saturated NaHCO3 solution, the reaction mixture was diluted with ether and washed with water. The organic layer was dried with anhydrous Na2SO4 and concentrated. The crude product was purified by column chromatography (ethyl acetate/hexane as eluent) to give 3-methyl-1H-indole-1,3-dicarboxylic acid-1-tert-butyl ester in 98% yield.

References

[1] Patent: US2009/215828, 2009, A1. Location in patent: Page/Page column 13
[2] Patent: WO2009/103552, 2009, A1. Location in patent: Page/Page column 31
[3] Research on Chemical Intermediates, 2017, vol. 43, # 3, p. 1355 - 1363
[4] Tetrahedron, 2003, vol. 59, # 6, p. 747 - 754
[5] Chemistry - A European Journal, 2010, vol. 16, # 48, p. 14534 - 14544

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER Preparation Products And Raw materials

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER Suppliers

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INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER Spectrum

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER METHYL 1-BOC-1H-INDOLE-3-CARBOXYLATE 1H-Indole-1,3-dicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester 1-tert-Butyl 3-Methyl 1H-indole-1,3-dicarboxylate methyl 1-tert-butoxycarbonyl-1H-indole-3-carboxylate tert-butyl methyl 1H-indole-1,3-dicarboxylate 338760-26-2