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3,5-Difluorobenzyl bromide

3,5-Difluorobenzyl bromide Structure
3,5-Difluorobenzyl bromide structure
CAS No.
141776-91-2
Chemical Name:
3,5-Difluorobenzyl bromide
Synonyms
1-(BROMOMETHYL)-3,5-DIFLUOROBENZENE;5-Fluoro-2-formylphenylboronic acid;2-Formyl-5-(trifluoromethoxy)phenylboronic acid;CAS:141776-91-2;3,5-DIFLUOROBENZYL BROMIDE;3,5-Bifluorobenzyl bromide;3,5-DIFLROROBENZYL BROMIDE;α-bromo-3,5-difluorotoluene;à-bromo-3,5-difluorotoluene;3,5-Difluorobenzylbromide98%
CBNumber:
CB0109385
Molecular Formula:
C7H5BrF2
Molecular Weight:
207.02
MDL Number:
MFCD00010304
MOL File:
141776-91-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:05:13
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3,5-Difluorobenzyl bromide Properties

Boiling point 65 °C4.5 mm Hg(lit.)
Density 1.6 g/mL at 25 °C(lit.)
refractive index n20/D 1.521(lit.)
Flash point 179 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
color Colorless to Orange to Green
Specific Gravity 1.62
Sensitive Lachrymatory
BRN 7422062
InChI InChI=1S/C7H5BrF2/c8-4-5-1-6(9)3-7(10)2-5/h1-3H,4H2
InChIKey KVSVNRFSKRFPIL-UHFFFAOYSA-N
SMILES C1(CBr)=CC(F)=CC(F)=C1
CAS DataBase Reference 141776-91-2(CAS DataBase Reference)
NIST Chemistry Reference 3,5-Difluorobenzyl bromide(141776-91-2)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,Xi
Risk Statements  34-36-43
Safety Statements  26-36/37/39-45-27-36/37
RIDADR  UN 3265 8/PG 2
WGK Germany  3
Hazard Note  Corrosive/Lachrymatory
HazardClass  8
PackingGroup  III
HS Code  29039990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 1

3,5-Difluorobenzyl bromide price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 290319 3,5-Difluorobenzyl bromide 98% 141776-91-2 5g $51.3 2026-04-30 Buy
Sigma-Aldrich 290319 3,5-Difluorobenzyl bromide 98% 141776-91-2 25g $150 2026-04-30 Buy
TCI Chemical D2631 3,5-Difluorobenzyl Bromide >98.0%(GC) 141776-91-2 5g $50 2026-04-30 Buy
TCI Chemical D2631 3,5-Difluorobenzyl Bromide >98.0%(GC) 141776-91-2 25g $166 2026-04-30 Buy
Usbiological 232306 3,5-Difluorobenzyl bromide 99+% (GC) ≥99%(GC) 141776-91-2 5g $156 2026-06-03 Buy
Product number Packaging Price Buy
290319 5g $51.3 Buy
290319 25g $150 Buy
D2631 5g $50 Buy
D2631 25g $166 Buy
232306 5g $156 Buy

3,5-Difluorobenzyl bromide Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

3,5-Difluorobenzyl bromide is a kind of important medicine intermediate. 

Synthesis

Triphenylphosphine (2.75 g, 10.5 mmol) and carbon tetrabromide (3.48 g, 10.5 mmol) were added to a dry reaction flask followed by the addition of 25 mL of ether and the resulting mixture was stirred at room temperature for 30 min, then an ether solution of 3,5-difluorobenzenemethanol (10.5 mmol) was slowly added to the above mentioned system and the reaction mixture was continued to be stirred at 25C for 40 minutes. At the end of the reaction, petroleum ether was added to the reaction system, and a white precipitate of triphenylphosphine oxide was observed. Most of the triphenylphosphine oxide was removed by filtration, and the obtained filtrate was concentrated in vacuum, and finally, hexane was used as the eluent, and the residue was separated and purified by silica gel chromatography to obtain the target product of 3,5-difluorobenzyl bromide.

3,5-Difluorobenzyl bromide synthesis

79538-20-8
141776-91-2
Synthesis of 3,5-Difluorobenzyl bromide from 3,5-Difluorobenzyl alcohol

3,5-Difluorobenzyl bromide Preparation Products And Raw materials

Raw materials

1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide 3,5-Difluorobenzyl alcohol

Preparation Products

5-(3,5-difluorobenzyl)-2-fluorobenzonitrile 2,6-difluoro-4-methylbenzoic acid DL-3,5-DIFLUOROPHENYLALANINE 3,5-DIFLUOROBENZYLMETHYLSULFONE tert-Butyl 1-(3,5-difluorobenzyl)piperidin-4-ylcarbamate
N-ACETYL-3-(3,5-DIFLUOROPHENYL)-DL-ALANINE

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3,5-Difluorobenzyl bromide Suppliers

Global( 306)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Weifang QianJin Fine Chemical Co., Ltd. 18753684562 1577399715@qq.COM China 1772 55
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Supplier Advantage
Changzhou Huanling Chemical Co., Ltd. 68
Weifang QianJin Fine Chemical Co., Ltd. 55
Tianjin Jinyuda Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65

View Lastest Price from 3,5-Difluorobenzyl bromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Difluorobenzyl bromide pictures 2026-09-10 3,5-Difluorobenzyl bromide
141776-91-2
 $5.00 1kg ≥99% 100mt/year Jinan Finer Chemical Co., Ltd
3,5-Difluorobenzyl bromide pictures 2026-09-02 3,5-Difluorobenzyl bromide
141776-91-2
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
3,5-Difluorobenzyl bromide pictures 2026-03-20 3,5-Difluorobenzyl bromide
141776-91-2
 $8.90 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd

3,5-Difluorobenzyl bromide Spectrum

3,5-Difluorobenzyl bromide(141776-91-2)1HNMR3,5-Difluorobenzyl bromide(141776-91-2)FT-IR3,5-Difluorobenzyl bromide(141776-91-2)Raman3,5-Difluorobenzyl bromide(141776-91-2)IR

141776-91-2(3,5-Difluorobenzyl bromide)Related Search:

2,3-Difluorobenzyl bromide Rocuronium bromide Dibromomethane Sodium bromate 1,2-Difluorobenzene
Ethidium bromide Allyl bromide 4-Trifluoromethylbenzyl chloride Vecuronium bromide 4-Bromobenzotrifluoride
Dimidium bromide Decabromodiphenyl Ethane Ethyl bromodifluoroacetate 3,5-DIFLUOROBENZYL CHLORIDE 3,5-Difluoronitrobenzene
Methyl bromide 2,3,5,6-TETRAFLUOROBENZYL BROMIDE 2,3,4,5-TETRAFLUOROBENZYL BROMIDE

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3,5-DIFLUOROBENZYL BROMIDE ALPHA-BROMO-3,5-DIFLUOROTOLUENE à-bromo-3,5-difluorotoluene α-bromo-3,5-difluorotoluene 3,5-Difluorobenzyl bromide 98% 3,5-Difluorobenzylbromide98% 2-Benzyloxy-5-formylphenylboronic acid 2-Formyl-5-(trifluoromethoxy)phenylboronic acid alpha-Bromo-3,5-difluorotoluene,98% 4-Hydroxymethyl-3-methylphenylboronic acid 3,5-Difluorobenzyl bromide,α-Bromo-3,5-difluorotoluene 3,5-Bifluorobenzyl bromide 1-(Bromomethyl)-3,5-difluorobenzene, alpha-Bromo-3,5-difluorotoluene alpha-BroMo-3,5-difluorotoluene, 98% 1GR 3,5-DifluorobenzylBromide> Benzene, 1-(bromomethyl)-3,5-difluoro- 3,5-Difluorobenzyl bromide ISO 9001：2015 REACH 3,5-DIFLROROBENZYL BROMIDE CAS:141776-91-2 1-(BROMOMETHYL)-3,5-DIFLUOROBENZENE 5-Fluoro-2-formylphenylboronic acid 141776-91-2 141779-91-2 C17H22B2ClNO4 C8H10BFO4 C15H20BBrO4 C18H29BClNO2 BENZYL HALIDE Organic Building Blocks Halogenated Hydrocarbons Building Blocks Aryl C7 Aryl Fluorinated Building Blocks C7 Chemical Synthesis Fluorinated Building Blocks Halogenated Hydrocarbons Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Fluorine series Aromatic Halides (substituted) Miscellaneous Aryl Organohalides Catalysts-Ligands Organoborons Sulfonamide Amide Building Blocks Fluorinated Boronic ester Boronic acid Alkoxy Ester Fluoro-contained benzyl bromide series