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3,4'-Oxydianiline

3,4'-Oxydianiline Structure
3,4'-Oxydianiline structure
CAS No.
2657-87-6
Chemical Name:
3,4'-Oxydianiline
Synonyms
3-(4-aminophenoxy)aniline;3,4'-ODA;3,4'-Diaminodiphenyl ether;DAPE;3,4'-DPE;JACS-2657-87-6;3,4'-Oxydianiline;3,4'-0xydianiline;3,4'-Diaminodiphenyl;3,4'-Oxybis(aniline)
CBNumber:
CB0109512
Molecular Formula:
C12H12N2O
Molecular Weight:
200.24
MDL Number:
MFCD00036097
MOL File:
2657-87-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-04 16:00:12
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3,4'-Oxydianiline Properties

Melting point 67-71 °C(lit.)
Boiling point 206.5 °C1 mm Hg(lit.)
Density 1.1131 (rough estimate)
refractive index 1.6660 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform, Methanol
pka 4.78±0.10(Predicted)
form Solid
color Off-White
Stability Light sensitive
InChI InChI=1S/C12H12N2O/c13-9-4-6-11(7-5-9)15-12-3-1-2-10(14)8-12/h1-8H,13-14H2
InChIKey ZBMISJGHVWNWTE-UHFFFAOYSA-N
SMILES C1(N)=CC=CC(OC2=CC=C(N)C=C2)=C1
CAS DataBase Reference 2657-87-6(CAS DataBase Reference)
UNSPSC Code 12162002
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H317-H341-H351-H361-H410
Precautionary statements  P201-P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN2811 - class 6.1 - PG 2 - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany  3
HazardClass  6.1
HS Code  29222990
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Carc. 2
Muta. 2
Repr. 2
Skin Sens. 1
Limited Quantities 0.5 Kg (solid)
Excepted Quantities Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)
NFPA 704
0
2 0

3,4'-Oxydianiline price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 476307 3,4′-Oxydianiline 97% 2657-87-6 10g $137 2026-04-30 Buy
TCI Chemical D1924 3,4'-Diaminodiphenyl Ether >97.0%(GC)(T) 2657-87-6 5g $56 2026-04-30 Buy
TCI Chemical D1924 3,4'-Diaminodiphenyl Ether >97.0%(GC)(T) 2657-87-6 25g $219 2026-04-30 Buy
Usbiological 274291 3,4'-Diaminodiphenyl ether Asreported 2657-87-6 10g $333 2026-06-03 Buy
Usbiological 274291 3,4'-Diaminodiphenyl ether Asreported 2657-87-6 25g $470 2026-06-03 Buy
Product number Packaging Price Buy
476307 10g $137 Buy
D1924 5g $56 Buy
D1924 25g $219 Buy
274291 10g $333 Buy
274291 25g $470 Buy

3,4'-Oxydianiline Chemical Properties, Uses, Production

Description

3,4'-Oxydianiline (3,4'-ODA) is a phenyl ether derivative capped at both ends with two amines in the para and meta positions. 3,4'-ODA is commonly used in the synthesis of polyimides which have multifunctional properties.3,4'-ODA is transparent and can be used as a substrate for displays. Polyimides are transparent and can be used as substrates for displays. 3,4'-ODA can also be used to synthesise organic porous materials with a BET surface area of up to 351 m2/g. Polyetherimide membranes made from this diamine structural unit show good permeation during water-isopropanol separation.

Uses

3,4'-Oxydianiline is an ether organic substance and can be used as a pharmaceutical intermediate.

Uses

3,4''-Diaminodiphenyl Ether, can be used for the synthesis of asymmetric soluble polyimides. It can also be used as a spacer in the preparation of glycine-based molecular tongs as inhibitors of β-amyloid peptide Aβ1-40 aggregation in vitro.

Application

3,4'-Oxydianiline (3,4'-ODA) is a diphenylamine compound with a purity of up to 99%. It is commonly used as a synthetic raw material, reacting with acid anhydrides to form polyimide films or foams. It is also used in the production of co-p-aramid fibres. Co-p-aramid fibres synthesised using 3,4'-ODA as the sole comonomer exhibit tensile moduli and tensile strengths of 80.4 and 3.1 GPa, respectively. These aramid fibres are widely used in bulletproof vests, optical cables and the aerospace industry.

Materials Uses

The addition of 3,4'-Oxydianiline(3,4′-ODA) significantly alters the microcellular morphology and macroscopic volume stability of polyimide by introducing flexible segments and changing the gas release kinetics during the foaming process.[2]

Synthesis

3-AMINO-4'-NITRODIPHENYL ETHER

22528-34-3

3,4'-Oxydianiline

2657-87-6

GENERAL STEPS: The hydrogenation reaction was carried out in a 100 mL reaction flask equipped with an FB generator without additional stirring. 3-Amino-4'-nitrodiphenyl ether (10 mmol) was dissolved in ethyl acetate (80 mL) and subsequently heated to 30 °C. H2-FB was introduced into the reaction system in the presence of palladium alumina spheres (0.5% Pd, 2-4 mm, 0.3 mmol, 3 mol%) using a FB generator (MA3-FS) at a flow rate of 5 mL/min. The reaction progress was monitored by sampling the reaction periodically by GC analysis. Upon completion of the hydrogenation reaction, ethyl acetate was removed by vacuum evaporation to obtain high purity 3,4'-diaminodiphenyl ether.

References

[1] Synlett,  2017,  vol. 28,  # 16,  p. 2184 - 2188
[2] YIN LI. Effects of 3,4′-oxydianiline on the structures and properties of a novel aromatic polyimide foam[J]. Journal of Applied Polymer Science, 2012, 125 5: 4128-4134. DOI:10.1002/app.35683.

3,4'-Oxydianiline synthesis

22528-34-3
2657-87-6
Synthesis of 3,4'-Oxydianiline from 3-Amino-4'-nitrodiphenyl ether

3,4'-Oxydianiline Preparation Products And Raw materials

Raw materials

3-Amino-4'-nitrodiphenyl ether Palladium on strontium carbonate, reduced 4-Iodoaniline Aluminum oxide N,N-Dimethylformamide
Hydrogen 3-Aminophenol

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Preparation Products

3,4'-Oxydianiline Suppliers

Global Suppliers ( 375)
Supplier Tel Email Country ProdList Advantage
Heynova (Shanghai) New Material Technology CO., Ltd 17821102608 zoe@heynovachem.com China 211 58
Changzhou Sunlight Pharmaceutical Co., Ltd 519-83131668 15995063688 info@sunlightchem.com China 100 69
CHINATECH(TIANJIN) CHEMICAL CO.,LTD. 18222205756 sales6@chinatechem.com China 100 58
Suzhou Zejun Biotechnology Co., Ltd. 13814894981 749428581@qq.com China 238 58
Sinocey New Materials Technology Co., Ltd. 18964289680 marketing@sinocey.com China 2 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Supplier Advantage
Heynova (Shanghai) New Material Technology CO., Ltd 58
Changzhou Sunlight Pharmaceutical Co., Ltd 69
CHINATECH(TIANJIN) CHEMICAL CO.,LTD. 58
Suzhou Zejun Biotechnology Co., Ltd. 58
Sinocey New Materials Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
future industrial shanghai co., ltd 65
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55

Related Questions

Ask a question
Q:What is the use and preparation of 3,4'-Oxydianiline?Zora - Oct 14,2025
A: 3,4'-Oxydianiline is typically used for synthesizing polyimides with multi-functionalities. The preparation of 3,4'-Oxydianiline is as follows:The hydrogenation reaction was carried out in a 100 mL reaction flask equipped with an FB generator without additional stirring. 3-Amino-4'-nitrodiphenyl ether (10 mmol) was dissolved in ethyl acetate (80 mL) and subsequently heated to 30 °C. H2-FB was introduced into the reaction system in the presence of palladium alumina spheres (0.5% Pd, 2-4 mm, 0.3 mmol, 3 mol%) using a FB generator (MA3-FS) at a flow rate of 5 mL/min. Upon completion of the hydrogenation reaction, ethyl acetate was removed by vacuum evaporation to obtain high purity 3,4'-diaminodiphenyl ether.

View Latest Price from 3,4'-Oxydianiline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4'-Oxydianiline pictures 2026-09-14 3,4'-Oxydianiline
2657-87-6
 0.99 RongNa Biotechnology Co.,Ltd
3,4'-Oxydianiline pictures 2026-09-11 3,4'-Oxydianiline
2657-87-6
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
3,4'-Oxydianiline pictures 2026-09-07 3,4'-Oxydianiline
2657-87-6
 1kg 99%min 20tons HANGZHOU HAILAN CHEMICAL CO.,LTD.

3,4'-Oxydianiline Spectrum

3,4'-Oxydianiline(2657-87-6)MS3,4'-Oxydianiline(2657-87-6)1HNMR3,4'-Oxydianiline(2657-87-6)13CNMR3,4'-Oxydianiline(2657-87-6)IR13,4'-Oxydianiline(2657-87-6)IR2

2657-87-6 (3,4'-Oxydianiline) Related Search:

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3,4'-Dichlorodiphenyl ether Triclosan Diphenyl ether 2-Anilino-6-dibutylamino-3-methylfluoran 7-Anilino-3-diethylamino-6-methyl fluoran
2'-(Dibenzylamino)-6'-(diethylamino)fluoran Diphenylamine 3-Amino-4'-nitrodiphenyl ether 2'-(2-Chloroanilino)-6'-(dibutylamino)fluoran (3-Nitro-phenyl)-(4-nitro-phenyl)-ether
3,4,4'-Triaminodiphenyl ether N-[3-(4-Amino-2-chlorophenoxy)phenyl]-N,N-dimethylamine N-[3-(4-Amino-2-fluorophenoxy)phenyl]-N,N-dimethylamine

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4-(3-AMINO-PHENOXY)-PHENYLAMINE 3,4'-DPE 3,4'-DIAMINOPHENYL ETHER 3,4'-Oxydianiline(3,4'-ODA) 3,4'-DiaminodiphenylEther>99.0% 3,4-DIAMINODIPHENYL ETHER (3,4-DAPE) 3,4'-Diaminodiphenyl 3,4''-DIAMINODIPHENYL ETHER / 3,4''-OXYDIANILINE 3,4''-DIAMINODIPHENYL ETHER 97+% 3,4''-OXYDIANILINE (3,4''-DIAMINODIPHENYLETHER) 3,4'-Diaminodiphenyl Ether (3,4-ODA) 3-(4-aminophenoxy)aniline,3,4'-Oxydianiline 3,4'-Oxybis(aniline) 4-(3-Aminophenoxy)aniline p-(m-Aminophenoxy)aniline 3,4'-Oxydianiline [3-(4-aminophenoxy)phenyl]amine 3-(4-azanylphenoxy)aniline 3,4'-Diaminodiphenyl Ether ,99% 4'-DiaMino diphenylether JACS-2657-87-6 3,4'-DiaminodiphenylEther> Benzenamine, 3-(4-aminophenoxy)- 3,4'-Oxydianiline Manufacturer CAS NO.2657-87-6 3,4'-Oxydianiline(3,4'-ODA 3,4'-0xydianiline 3,4'-Diaminodiphenyl Ether (3,4'-ODA) 3,4′-Diaminodiphenyl ether, CAS 2657-87-6 3,4'-Oxydianiline (3,4'-ODA) - 99.5 Purity 3,4'-Oxydianiline (3,4'-ODA) - 99.95 Purity 3-(4-aminophenoxy)aniline 3,4'-Diaminodiphenyl ether 3,4'-ODA DAPE 2657-87-6 Diphenyl Ethers (for High-Performance Polymer Research) Reagent for High-Performance Polymer Research Monomers Primary Amines Biphenyl & Diphenyl ether Amines Miscellaneous Diphenyl Ethers (for High-Performance Polymer Research) Functional Materials Reagent for High-Performance Polymer Research Amine Monomers 2657-87-6 PI