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VU 0463841

VU 0463841 Structure
VU 0463841 structure
CAS No.
1439095-16-5
Chemical Name:
VU 0463841
Synonyms
VU0463841;VU-0463841;VU 0463841
CBNumber:
CB011075608
Molecular Formula:
C13H8ClFN4O
Molecular Weight:
290.68
MDL Number:
MOL File:
1439095-16-5.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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VU 0463841 Chemical Properties,Uses,Production

Description

VU0463841 is a negative allosteric modulators of mGlu5.

Uses

VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research[1].

IC 50

mGlu5 Receptor: 13 nM (IC50)

References

[1] Russell J Amato, et al. Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction. ACS Chem Neurosci. 2013 Aug 21;4(8):1217-28. DOI:10.1021/cn400070k

VU 0463841 Preparation Products And Raw materials

Raw materials

Preparation Products

VU 0463841 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39040 58
Wuhan Han Sheng New Material Technology Co.，Ltd 		+8617798174412 admin01@hsnm.com.cn China 2097 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19957 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29430 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Wuhan Han Sheng New Material Technology Co.，Ltd 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58

View Lastest Price from VU 0463841 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VU0463841 pictures 2026-04-21 VU0463841
1439095-16-5
 US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • VU0463841 pictures
  • VU0463841
    1439095-16-5
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.

1439095-16-5(VU 0463841)Related Search:

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(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide Urea, N-(3,4-difluorophenyl)-N'-[3-methyl-1-(phenylmethyl)-1H-pyrazol-5-yl]- VU-0486321 VU0238441 VU0483605
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VU 0463841 VU0463841 VU-0463841 1439095-16-5