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Vitexilactone

CAS No.
61263-49-8
Chemical Name:
Vitexilactone
Synonyms
4-[2-[(4aα)-4β-Acetoxy-1-hydroxy-2α,5,5,8aβ-tetramethyldecalin-1β-yl]ethyl]-2(5H)-furanone;4-[2-[(1R,4aα)-Decahydro-4β-acetoxy-1α-hydroxy-2α,5,5,8aβ-tetramethylnaphthalen-1-yl]ethyl]furan-2(5H)-one;2(5H)-Furanone, 4-[2-[(1R,2R,4R,4aS,8aS)-4-(acetyloxy)decahydro-1-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl]ethyl]-;(1R,3R,4R,4aS,8aS)-4-Hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2,5-dihydro-3-furanyl)ethyl]decahydro-1-naphthalenyl acetate;[(1R,3R,4R,4aS,8aS)-4-hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2H-furan-3-yl)ethyl]-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate
CBNumber:
CB01117703
Molecular Formula:
C22H34O5
Molecular Weight:
378.5
MDL Number:
MFCD07779142
MOL File:
61263-49-8.mol
Last updated:2025-04-18 09:51:22

Vitexilactone Properties

Melting point 148~149℃
Boiling point 501.5±40.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 14.51±0.70(Predicted)
FDA UNII 8HP9QLE96R

Vitexilactone price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation PXT0001314 VITEXILACTONE 98.00% 61263-49-8 10MG $1039.5 2021-12-16 Buy
Arctom CFN97047 Vitexilactone 61263-49-8 5mg $593 2021-12-16 Buy
Product number Packaging Price Buy
PXT0001314 10MG $1039.5 Buy
CFN97047 5mg $593 Buy

Vitexilactone Chemical Properties,Uses,Production

Uses

Vitexilactone is a diterpenoid that can be isolated from the leaves of Vitex negundo L. Vitexilactone shows antimicrobial activity towards E. coli. Vitexilactone induces cell apoptosis and inhibits cell cycle of cancer cells. Vitexilactone can be used for the research of cancer[1][2].

Definition

ChEBI: A labdane diterpenoid that is isolated from the fruits of Vitex trifolia L. and Vitex agnus-castus

target

HIV | NADPH-oxidase | Antifection

References

[1] Sichaem J, et al. A new labdane-type diterpenoid from the leaves of Vitex negundo L. Nat Prod Res. 2021 Jul;35(14):2329-2334. DOI:10.1080/14786419.2019.1672687
[2] Li WX, et al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr;7(2):95-105. DOI:10.1080/10286020310001617165

Vitexilactone Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,3R,4R,4aS,8aS)-4-Hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2,5-dihydro-3-furanyl)ethyl]decahydro-1-naphthalenyl acetate 4-[2-[(1R,4aα)-Decahydro-4β-acetoxy-1α-hydroxy-2α,5,5,8aβ-tetramethylnaphthalen-1-yl]ethyl]furan-2(5H)-one 4-[2-[(4aα)-4β-Acetoxy-1-hydroxy-2α,5,5,8aβ-tetramethyldecalin-1β-yl]ethyl]-2(5H)-furanone [(1R,3R,4R,4aS,8aS)-4-hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2H-furan-3-yl)ethyl]-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate 2(5H)-Furanone, 4-[2-[(1R,2R,4R,4aS,8aS)-4-(acetyloxy)decahydro-1-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl]ethyl]- 61263-49-8