ChemicalBook >> CAS DataBase List >>H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH structure

CAS No.: 121204-87-3

Chemical Name:: H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH

Synonyms: 4 ALA ET-1;[Ala1,3,11,15]ET-1;ASASSLMDKEAVYFAHLDIIW;[ALA1,3,11,15]-ENDOTHELIN;[ALA1,3,11,15]ENDOTHELIN-I;(ALA1,3,11,15)-ENDOTHELIN-1;endothelin 1, Ala(1,3,11,15)-;[Ala1,3,11,15]-Endothelin (53-63);[ALA1,3,11,16]-ENDOTHELIN 1, HUMAN;[ALA1,3,11,15] ENDOTHELIN-1, HUMAN

CBNumber:: CB0121062

Molecular Formula:: C109H163N25O32S

Molecular Weight:: 2367.67

MDL Number:: MFCD00143562

MOL File:: 121204-87-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:43:53

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H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH Properties

Boiling point	2391.5±65.0 °C(Predicted)
Density	1.319±0.06 g/cm3(Predicted)
storage temp.	-20°C
form	Solid
Water Solubility	Soluble to 1 mg/ml in water
InChIKey	NRTWVLDGYXCWHD-IGKRDWOESA-N
UNSPSC Code	12352200
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300+H330
Precautionary statements	P260-P264-P284-P301+P310+P330-P304+P340+P310-P403+P233
PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E6877	[Ala1,3,11,15]-Endothelin 1	121204-87-3	0.5mg	$457	2024-03-01	Buy
Usbiological	254579	[Ala1,3,11,15]-Endothelin Asreported	121204-87-3	500ug	$466	2026-06-03	Buy
Biosynth	FA108867	(Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt	121204-87-3	2000ug	$900	2026-06-04	Buy
Biosynth	FA108867	(Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt	121204-87-3	1000ug	$900	2026-06-04	Buy
Biosynth	FA108867	(Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt	121204-87-3	500ug	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
E6877	0.5mg	$457	Buy
254579	500ug	$466	Buy
FA108867	2000ug	$900	Buy
FA108867	1000ug	$900	Buy
FA108867	500ug	$900	Buy

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH Chemical Properties, Uses, Production

Uses

[Ala^1,3,11,15]-Endothelin 1 may be used to assess the effects of endothelin-1 and [Ala^1,3,11,15]-endothelin 1 produced by ETA and ETB receptors, in the presence of BQ-123, in anaesthetized rat.

General Description

[Ala^1,3,11,15]-Endothelin 1 is a linear endothelin (ET)-1 analogue, and acts as an ETB receptor agonist. ET-1 is a peptide that acts as both, a vasodilator and a vasoconstrictor. It is a ligand for ET receptor, which is of two types, ETA and ETB. ETB receptor is found in the vascular endothelial cells of cardiovascular tissues.

Biochem/physiol Actions

Selective agonist for ETB endothelin receptors.

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH Suppliers

Global Suppliers ( 74)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Creative Peptides		info@creative-peptides.com	United States	6083	56
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Sigma-Aldrich	80
Creative Peptides	56
Shanghai YuanYe Biotechnology Co., Ltd.	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55

121204-87-3 (H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH) Related Search:

H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH ([125I]-Tyr)-endothelin-1 (human, bovine, dog, mouse, porcine, rat) Ac-Gly-Trp-OH H-Ile-Trp-OH H-Gly-Gly-Trp-OH

Endothelin-1 [ALA1,3,11,15] [3-(125I)tyr] (human) Endothelin (16-21) Dipeptide-2 Endothelin-1 (human, porcine) BQ-3020

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ASASSLMDKEAVYFAHLDIIW 4 ALA ET-1 [ALA1,3,11,15]-ENDOTHELIN (ALA1,3,11,15)-ENDOTHELIN-1 [ALA1,3,11,15] ENDOTHELIN-1, HUMAN [ALA1,3,11,15]ENDOTHELIN-I [ALA1,3,11,16]-ENDOTHELIN 1, HUMAN ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP endothelin 1, Ala(1,3,11,15)- [Ala1,3,11,15]ET-1 L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-Asp-L-Lys-L-Glu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-Asp-L-Ile-L-Ile-L-Trp-OH L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-αAsp-L-Lys-L-αGlu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-αAsp-L-Ile-L-Ile-L-Trp-OH ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP: ASASSLMDKEAVYFAHLDIIW (Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH trifluoroacetate salt L-Tryptophan, L-alanyl-L-seryl-L-alanyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl- H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP [Ala1,3,11,15]-Endothelin (53-63) (Ala?·?·??·??)-Endothelin-1 trifluoroacetate salt (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S)-17-((1H-imidazol-5-yl)methyl)-2-((1H-indol-3-yl)methyl)-41-((2S,5S,8S,11S,14S,17S,20S)-20-amino-8,11,17-tris(hydroxymethyl)-5-isobutyl-14-methyl-2-(2-(methylthio)ethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazahenicosanamido)-38-(4-aminobutyl)-23-benzyl-5,8-di((S)-sec-butyl)-35-(2-carboxyethyl)-11-(carboxymethyl)-26-(4-hydroxybenzyl)-14-isobutyl-29-isopropyl-20,32-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxo-3,6,9,12,15,18,2 [Ala^1,3,11,15]-Endothelin 1 H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH 121204-87-3 C109H163O32N25S C109H163N25O32S Biochemicals and Reagents Amino Acids and Peptides Agonist BioChemical Endothelins Peptides Endothelin receptor Agonists Endothelins Peptides for Cell Biology peptide