(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
- CAS No.
- 191919-01-4
- Chemical Name:
- (Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
- Synonyms
- 8-iso-15-keto-PGF2alpha;LOLJEILMPWPILA-RLXHZABYSA-N;8-iso-15-keto Prostaglandin F2α;Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,8β,9α,11α,13E)-;(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
- CBNumber:
- CB01235658
- Molecular Formula:
- C20H32O5
- Molecular Weight:
- 352.47
- MDL Number:
- MOL File:
- 191919-01-4.mol
- MSDS File:
- SDS
| Boiling point | 535.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.149±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | 10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml |
| pka | 4.76±0.10(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H360-H336 | |||||||||
| Precautionary statements | P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16390 | 8-iso-15-keto Prostaglandin F2α ≥95% | 191919-01-4 | 50μg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 16390 | 8-iso-15-keto Prostaglandin F2α ≥95% | 191919-01-4 | 100μg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 16390 | 8-iso-15-keto Prostaglandin F2α ≥95% | 191919-01-4 | 500μg | $432 | 2026-04-30 | Buy |
| Cayman Chemical | 16390 | 8-iso-15-keto Prostaglandin F2α ≥95% | 191919-01-4 | 1mg | $169 | 2024-03-01 | Buy |
(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid Chemical Properties, Uses, Production
Uses
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.[Cayman Chemical]
Definition
ChEBI: 8-iso-15-keto-PGF2a is a prostanoid.
IC 50
FP
(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
View Latest Price from (Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | 8-iso-15-keto Prostaglandin F2α
191919-01-4
|
$613.00 | 10g | TargetMol Chemicals Inc. |
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- 8-iso-15-keto Prostaglandin F2α
191919-01-4
- $613.00
- TargetMol Chemicals Inc.







