Misoprostol Acid
- CAS No.
- 112137-89-0
- Chemical Name:
- Misoprostol Acid
- Synonyms
- MISOPROSTOL ACID;MISOPROSTOL FREE ACID;8-iso Misoprostol acid;Misoprostol Acid USP/EP/BP;Misoprostol acid,racemic mixture;Misoprostol Acid, Technical Grade 65%;Misoprostol Acid (10 mg in 1 mL Methyl Acetate);(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E;(+-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDINE1;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1
- CBNumber:
- CB0713294
- Molecular Formula:
- C21H36O5
- Molecular Weight:
- 368.51
- MDL Number:
- MFCD07772001
- MOL File:
- 112137-89-0.mol
- MSDS File:
- SDS
| Boiling point | 538.3±50.0 °C(Predicted) |
|---|---|
| Density | 1.118±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform |
| form | Yellow viscous oil. |
| pka | 4.77±0.10(Predicted) |
| color | Pale Yellow |
| Stability | Temperature Sensitive |
| FDA UNII | 12Z0SU967A |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335-H361 | |||||||||
| Precautionary statements | P201-P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 45-60-61-25-36/37/38 | |||||||||
| Safety Statements | 53-22-36/37/39-45-26 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| HazardClass | 6.1 | |||||||||
| NFPA 704 |
|
Misoprostol Acid price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M6932 | Misoprostol free acid ≥90% | 112137-89-0 | 1mg | $188 | 2024-03-01 | Buy |
| Alfa Aesar | J67475 | Misoprostol, free acid | 112137-89-0 | 1mg | $85.65 | 2024-03-01 | Buy |
| Alfa Aesar | J67475 | Misoprostol, free acid | 112137-89-0 | 5mg | $304 | 2021-12-16 | Buy |
| Cayman Chemical | 13821 | Misoprostol (free acid) ≥97% | 112137-89-0 | 1mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 13821 | Misoprostol (free acid) ≥97% | 112137-89-0 | 5mg | $249 | 2024-03-01 | Buy |
Misoprostol Acid Chemical Properties,Uses,Production
Description
Misoprostol is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-
Chemical Properties
Pale Yellow Gel
Uses
Misoprostol Acid is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
Uses
A metabolite of Misoprostol. Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration
Uses
A cytoprotective prostaglandin PGE1 analogue.
Biochem/physiol Actions
Misoprostol is a synthetic prostaglandin E1 (PGE1) analogue use to prevent non steroidal anti inflammatory drug-induced (NSAID) gastric ulcers; as a labor inducing and postpartum hemorrhage treatment agent.
in vivo
Unlike the Misoprostol, Misoprostol acid is detectable in plasma. Misoprostol is a lipophilic methyl ester prodrug and is readily metabolized to the free acid, which is the biologically active form. Misoprostol is used worldwide for a variety of indications in obstetrics and gynecology. Misoprostol has both gastric antisecretory and mucosal protective effects[1].
IC 50
EP
Misoprostol Acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32364 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7922 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38789 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1955 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Supplier | Advantage |
|---|---|
| Hubei xin bonus chemical co. LTD | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| sgtlifesciences pvt ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| J & K SCIENTIFIC LTD. | 76 |
| Cato Research Chemicals Inc. | 55 |
| Sigma-Aldrich | 80 |
| BOC Sciences | 65 |
View Lastest Price from Misoprostol Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Misoprostol acid
112137-89-0
|
US $140.00-1170.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Misoprostol acid
112137-89-0
- US $140.00-1170.00 / mg
- TargetMol Chemicals Inc.
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