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6-Bromo-4-indazolecarboxylic acid methyl ester

CAS No.
885518-49-0
Chemical Name:
6-Bromo-4-indazolecarboxylic acid methyl ester
Synonyms
Methyl 6-bromo-(1H)-indaz...;6-Bromo-4-indazolecarboxylic acid methyl ester;6-BroMo-1H-indazol-4-carboxylic acid Methyl ester;6-BroMo-1H-indazole-4-carboxylic acid Methyl ester;1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester;1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI)
CBNumber:
CB0128102
Molecular Formula:
C9H7BrN2O2
Molecular Weight:
255.07
MDL Number:
MFCD07781319
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:43:54

6-Bromo-4-indazolecarboxylic acid methyl ester Properties

Boiling point 395.9±22.0 °C(Predicted)
Density 1.709±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 11.21±0.40(Predicted)
Appearance light yellow solid
InChI InChI=1S/C9H7BrN2O2/c1-14-9(13)6-2-5(10)3-8-7(6)4-11-12-8/h2-4H,1H3,(H,11,12)
InChIKey FEPRHRPOKPTRQZ-UHFFFAOYSA-N
SMILES N1C2=C(C(C(OC)=O)=CC(Br)=C2)C=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HS Code  2933998090

6-Bromo-4-indazolecarboxylic acid methyl ester price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific W9107 Methyl 6-bromo-1H-indazole-4-carboxylate 99%(GC) 885518-49-0 1g $18 2026-06-04 Buy
AK Scientific W9107 Methyl 6-bromo-1H-indazole-4-carboxylate 99%(GC) 885518-49-0 5g $55 2026-06-04 Buy
AK Scientific W9107 Methyl 6-bromo-1H-indazole-4-carboxylate 99%(GC) 885518-49-0 10g $95 2026-06-04 Buy
AK Scientific W9107 Methyl 6-bromo-1H-indazole-4-carboxylate 99%(GC) 885518-49-0 25g $227 2026-06-04 Buy
AK Scientific J91322 Methyl 6-bromo-1H-indazole-4-carboxylate 95% 885518-49-0 1g $12 2026-06-04 Buy
Product number Packaging Price Buy
W9107 1g $18 Buy
W9107 5g $55 Buy
W9107 10g $95 Buy
W9107 25g $227 Buy
J91322 1g $12 Buy

6-Bromo-4-indazolecarboxylic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 6-bromo-4-indazolecarboxylate is mainly used as an organic synthesis intermediate and is widely used in drug development and chemical research.

Synthesis

Methyl 1-Acetyl-6-broMo-1H-indazole-4-carboxylate

1346597-55-4

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

885518-49-0

Step 6: Synthesis of methyl 6-bromo-1H-indazole-4-carboxylate To a stirred solution of methyl 1-acetyl-6-bromo-1H-indazole-4-carboxylate (18 g, 61.0 mmol) in methanol (350 mL) was slowly added 6N HCl (350 mL). The reaction mixture was stirred at 60 °C for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Subsequently, the reaction mixture was alkalized with saturated NaHCO3 solution to pH 8. The precipitated solid was collected by filtration and dried under vacuum. The dried solid was stirred in ether for 15 min, filtered again and dried to give methyl 6-bromo-1H-indazole-4-carboxylate (11 g, 71.7% yield).

References

[1] Patent: WO2012/118812, 2012, A2. Location in patent: Page/Page column 313
[2] Patent: CN105037360, 2016, B. Location in patent: Paragraph 0400; 0401; 0402

1346597-55-4
885518-49-0
Synthesis of 6-Bromo-4-indazolecarboxylic acid methyl ester from Methyl 1-Acetyl-6-broMo-1H-indazole-4-carboxylate
Global( 138)Suppliers
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Shanghai Xiannuo Biotechnology Co., Ltd. 021-50718719 13918719472 China 978 58
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Suzhou aihua pharmaceutical technology Co.,Ltd 13814852116 13814852116 373953886@qq.com China 22 58
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China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57

View Lastest Price from 6-Bromo-4-indazolecarboxylic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER pictures 2026-03-20 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
885518-49-0
$10.00 1kg 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER pictures 2025-05-26 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER
885518-49-0
$5.00 1kg 0.99 10000 Hebei Fengjia New Material Co., Ltd
Methyl 6-bromo-1H-indazole-4-carboxylate pictures 2024-04-24 Methyl 6-bromo-1H-indazole-4-carboxylate
885518-49-0
$1.00 1KG 99.91% 200000 Ouhuang Engineering Materials (Hubei) Co., Ltd

6-Bromo-4-indazolecarboxylic acid methyl ester Spectrum

6-BroMo-1H-indazol-4-carboxylic acid Methyl ester Methyl 6-bromo-(1H)-indaz... 1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester 6-BroMo-1H-indazole-4-carboxylic acid Methyl ester 1H-Indazole-4-carboxylic acid, 6-bromo-, methyl ester (9CI, ACI) 6-Bromo-4-indazolecarboxylic acid methyl ester 885518-49-0 Indazoles