Methyl 6-formylnicotinate
- CAS No.
- 10165-86-3
- Chemical Name:
- Methyl 6-formylnicotinate
- Synonyms
- METHY 6-FORMYLNICOTINATE;Methyl 6-formylnicotinate;Methyl 6-formylpyridin-3-carboxylate;Methyl 6-formylpyridine-3-carboxylate;methyl 2-formylpyridine-5-carboxylate;6-Formylpyridine-3-carboxylic acid methyl ester;3-Pyridinecarboxylic acid, 6-forMyl-, Methyl ester
- CBNumber:
- CB2347794
- Molecular Formula:
- C8H7NO3
- Molecular Weight:
- 165.15
- MDL Number:
- MFCD08275010
- MOL File:
- 10165-86-3.mol
- MSDS File:
- SDS
| Melting point | 115-116.7 °C |
|---|---|
| Boiling point | 273℃ |
| Density | 1.249 |
| Flash point | 119℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 1.68±0.10(Predicted) |
| color | Yellow to brown |
| InChI | InChI=1S/C8H7NO3/c1-12-8(11)6-2-3-7(5-10)9-4-6/h2-5H,1H3 |
| InChIKey | BZOWIADSJYMJJJ-UHFFFAOYSA-N |
| SMILES | C1=NC(C=O)=CC=C1C(OC)=O |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P260 |
| target organs | Respiratory system |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39-36 |
| WGK Germany | WGK 3 |
| HazardClass | IRRITANT |
| HS Code | 29333990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
Methyl 6-formylnicotinate price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 64498 | METHYL 6-FORMYLNICOTINATE 95% | 10165-86-3 | 0.25G | $93 | 2026-04-30 | Buy |
| AstaTech | 64498 | METHYL 6-FORMYLNICOTINATE 95% | 10165-86-3 | 1G | $183 | 2026-04-30 | Buy |
| AstaTech | 64498 | METHYL 6-FORMYLNICOTINATE 95% | 10165-86-3 | 5G | $563 | 2026-04-30 | Buy |
| Apolloscientific | OR303729 | Methyl 6-formylnicotinate >99% | 10165-86-3 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR303729 | Methyl 6-formylnicotinate >99% | 10165-86-3 | 1g | $67 | 2026-06-04 | Buy |
Methyl 6-formylnicotinate Chemical Properties, Uses, Production
Synthesis Reference(s)
Tetrahedron, 64, p. 688, 2008 DOI: 10.1016/j.tet.2007.11.030
Synthesis
56026-36-9
10165-86-3
General procedure for the synthesis of methyl 6-formylnicotinate from methyl 6-hydroxymethylnicotinate: a mixture of methyl 6-hydroxymethylnicotinate (7 g, 37 mmol) and manganese dioxide (32.3 g, 372 mmol) in dichloromethane (200 mL) was stirred and reacted for 4 hours at 20°C. After completion of the reaction, the mixture was filtered and the filtrate was concentrated. The residue was purified by silica gel column chromatography (petroleum ether/ethyl acetate = 5/1) to afford methyl 6-formylnicotinate (6 g, 97% yield). Mass spectral data: MS-ESI (m/z): 166.2 ([M + H]+) (LC-MS method C; retention time: 0.36 min).
References
[1] Patent: WO2014/114185, 2014, A1. Location in patent: Page/Page column 126
[2] Patent: US2014/206681, 2014, A1. Location in patent: Paragraph 0782
[3] Molecules, 2014, vol. 19, # 1, p. 102 - 121
[4] Patent: CN104418811, 2017, B. Location in patent: Paragraph 0234-0236
[5] Tetrahedron Letters, 2006, vol. 47, # 39, p. 7025 - 7029
Methyl 6-formylnicotinate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Nuokang Pharmaceutical Technology Co., Ltd. | 022-23989838 13810451150 | 44766350@qq.com | China | 2725 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Tianjin Derchemist Science & Technology Co., Ltd. | 22-58627059 13920586291 | zdcomcon@126.com | China | 4094 | 50 |
View Latest Price from Methyl 6-formylnicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-26 | Methyl 6-formylnicotinate
10165-86-3
|
1kg | 98% | BTC Nantong Pharmaceuticals Technology Co.,Ltd | |||
 |
2019-12-26 | METHYL 6-FORMYLNICOTINATE
10165-86-3
|
$1.00 | 1KG | 99% | 1000KGS | Career Henan Chemical Co |
-
- Methyl 6-formylnicotinate
10165-86-3
- 98%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
-
- METHYL 6-FORMYLNICOTINATE
10165-86-3
- $1.00
- 99%
- Career Henan Chemical Co
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