Methyl 6-bromopicolinate
- CAS No.
- 26218-75-7
- Chemical Name:
- Methyl 6-bromopicolinate
- Synonyms
- METHYL 6-BROMOPYRIDINE-2-CARBOXYLATE;Methyl-2-Bromo pyridine-6-carboxilate;RARECHEM AL BF 0899;METHYL 6-BROMOPICOLINATE;6-Bromopyridine-2-carboxyL;6-Bromopyridine-2-carboxylate;Methyl 6-broMo-2-pyridinecarboxylat;Methyl 6-Bromoyridine-2-carboxylate;Methy16-bromopyridine-2-carboxylate;METHYL 6-BROMO-2-PYRIDINECARBOXYLATE
- CBNumber:
- CB5273575
- Molecular Formula:
- C7H6BrNO2
- Molecular Weight:
- 216.03
- MDL Number:
- MFCD06203934
- MOL File:
- 26218-75-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl 6-Bromopyridine-2-carboxylate 97% | 650110 | 1g | $29.7 |
| Methyl 6-Bromopyridine-2-carboxylate 97% | 650110 | 5g | $148 |
| Methyl 6-Bromopyridine-2-carboxylate >98.0%(GC) | M2342 | 1g | $19 |
| Methyl 6-Bromopyridine-2-carboxylate >98.0%(GC) | M2342 | 5g | $54 |
| 2-Bromo-6-nicotinic acid methyl ester Asreported | 266451 | 2g | $333 |
| More product size | |||
| Melting point | 92-96 °C(lit.) |
|---|---|
| Boiling point | 289.7±20.0 °C(Predicted) |
| Density | 1.579±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| pka | -1.03±0.10(Predicted) |
| form | Crystalline Powder or Needles |
| color | White to pale pink to pale brown to yellow |
| InChI | InChI=1S/C7H6BrNO2/c1-11-7(10)5-3-2-4-6(8)9-5/h2-4H,1H3 |
| InChIKey | SGNCOKUHMXLGAH-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC(Br)=CC=C1 |
| CAS DataBase Reference | 26218-75-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335-H319 |
| Precautionary statements | P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| Hazard Note | Harmful/Irritant/Keep Cold |
| HS Code | 29333990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
Methyl 6-bromopicolinate price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 650110 | Methyl 6-Bromopyridine-2-carboxylate 97% | 26218-75-7 | 1g | $29.7 | 2023-06-20 | Buy |
| Sigma-Aldrich | 650110 | Methyl 6-Bromopyridine-2-carboxylate 97% | 26218-75-7 | 5g | $148 | 2021-12-16 | Buy |
| TCI Chemical | M2342 | Methyl 6-Bromopyridine-2-carboxylate >98.0%(GC) | 26218-75-7 | 1g | $19 | 2026-04-30 | Buy |
| TCI Chemical | M2342 | Methyl 6-Bromopyridine-2-carboxylate >98.0%(GC) | 26218-75-7 | 5g | $54 | 2026-04-30 | Buy |
| Usbiological | 266451 | 2-Bromo-6-nicotinic acid methyl ester Asreported | 26218-75-7 | 2g | $333 | 2026-06-03 | Buy |
Methyl 6-bromopicolinate Chemical Properties,Uses,Production
Chemical Properties
White to off-white solid
Uses
Methyl 6-bromopicolinate, also known as Methyl 6-bromopyridine-2-carboxylate, is a halogenated pyridine derivative that can be used in esterolysis reactions to form 6-Bromopicolinic acid.It can also be used in substitution reactions or cross-couplings to synthesise other pyridine compounds.
Synthesis
67-56-1
21190-87-4
26218-75-7
The general procedure for the synthesis of methyl 6-bromo-2-pyridinecarboxylate from methanol and 6-bromo-2-pyridinecarboxylic acid is as follows: 1. 6-bromo-2-pyridine carboxylic acid (6.000 g) was dissolved in methanol (180 mL) containing concentrated hydrochloric acid and heated to reflux. 2. Sulfuric acid (2 mL) was added and the reaction continued to reflux for 4 hours. 3. Upon completion of the reaction, the reaction mixture was cooled to about 0°C and concentrated. 4. Ammonia (4.8 mL) was added to the concentrated mixture. 5. The resulting solution was evaporated to give a white solid residue. 6. 6. The white solid was dissolved in a solvent mixture of dichloromethane (100 mL) and brine (100 mL), and the organic layer was separated with sufficient shaking. 7. The organic layer was dried with magnesium sulfate and the solvent was evaporated to give the white solid product methyl 6-bromo-2-pyridinecarboxylate (6.300 g, 98% yield). Product characterization data: 1H NMR (400 MHz, CDCl3) δ 4.00 (3H, s), 7.66-7.74 (2H, m), 8.07-8.13 (1H, m).
References
[1] Patent: WO2003/84917, 2003, A1. Location in patent: Page/Page column 26
[2] Journal of Agricultural and Food Chemistry, 2016, vol. 64, # 18, p. 3533 - 3537
[3] Patent: WO2017/9798, 2017, A1. Location in patent: Page/Page column 92
[4] Journal of Medicinal Chemistry, 2017, vol. 60, # 2, p. 722 - 748
[5] Inorganic Chemistry, 2018, vol. 57, # 13, p. 7512 - 7515
Methyl 6-bromopicolinate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Allfluoro pharmaceutical co. ltd. | +86-400-0216110 +86-15958047586 | sales@allfluoro.com | China | 11380 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8899 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14032 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 931 | 58 |
View Lastest Price from Methyl 6-bromopicolinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | Methyl 6-bromopyridine-2-carboxylate
26218-75-7
|
$34.00-210.00 | 10g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-08-06 | 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
26218-75-7
|
$6.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | Methyl 6-bromopicolinate
26218-75-7
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Methyl 6-bromopyridine-2-carboxylate
26218-75-7
- $34.00-210.00
- 0.98
- Shanghai UCHEM Inc.
-
- 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
26218-75-7
- $6.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Methyl 6-bromopicolinate
26218-75-7
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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