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Rac-Modipafant

Rac-Modipafant Structure
Rac-Modipafant structure
CAS No.
122956-68-7
Chemical Name:
Rac-Modipafant
Synonyms
UK-74505;Modipefant;rac-Modipafant;Modipafant racemate;(Rac) Modipafant,(Rac)Modipafant;ethyl 4-(2-chlorophenyl)-6-methyl-2-(4-{2-methylimidazo[4,5-c]pyridin-1-yl}phenyl)-5-[(pyridin-2-yl)carbamoyl]-1,4-dihydropyridine-3-carboxylate - [AC77674];ethyl 4-(2-chlorophenyl)-6-methyl-2-(4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate(WXG02205);4-(2-Chlorophenyl)-1,4-dihydro-6-Methyl-2-[4-(2-Methyl-1H-iMidazo[4,5-c]pyridin-1-yl)phenyl]-5-[(2-pyridinylaMino)carbonyl]-3-pyridinecarboxylic Acid Ethyl Ester;2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chlorophenyl)-5-[(2-pyridinylamino)carbonyl]-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester;3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-[(2-pyridinylamino)carbonyl]-, ethyl ester
CBNumber:
CB01310883
Molecular Formula:
C34H29ClN6O3
Molecular Weight:
605.09
MDL Number:
MFCD00864793
MOL File:
122956-68-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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Rac-Modipafant Properties

Density 1.34±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Store at -20°C
pka 12.14±0.70(Predicted)
form Solid
color Light yellow to yellow
FDA UNII 3QK4U86953

Rac-Modipafant price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0031421 (Rac)-Modipafant 98.15% 122956-68-7 1mg $287 2026-06-04 Buy
ChemScene CS-0031421 (Rac)-Modipafant 98.15% 122956-68-7 5mg $713 2026-06-04 Buy
ChemScene CS-0031421 (Rac)-Modipafant 98.15% 122956-68-7 10mg $1029 2026-06-04 Buy
ChemScene CS-0031421 (Rac)-Modipafant 98.15% 122956-68-7 25mg $1934 2026-06-04 Buy
ChemScene CS-0031421 (Rac)-Modipafant 98.15% 122956-68-7 50mg $3087 2026-06-04 Buy
Product number Packaging Price Buy
CS-0031421 1mg $287 Buy
CS-0031421 5mg $713 Buy
CS-0031421 10mg $1029 Buy
CS-0031421 25mg $1934 Buy
CS-0031421 50mg $3087 Buy

Rac-Modipafant Chemical Properties, Uses, Production

Uses

Modipafant is a novel and selective PAF antagonist with potent and prolonged oral activity.

in vivo

(Rac)-Modipafant (UK-74505) (10 mg/kg; p.o.; twice a day until day 10) prevents Severe Dengue Infection[3].
(Rac)-Modipafant exhibits highly selective, time-dependent inhibition of PAF-induced aggregation of rabbit washed platelets (IC50=26.3 and 1.12 nM after 0.25 and 60 min preincubation, respectively)[4].
(Rac)-Modipafant (5-20 mg/kg; p.o.) dose-dependently inhibits the Zymosan -induced articular hyperalgesia[5].

Animal Model:8- to 10-week-old BALB/c mice (DEN-2 strain infected)[3]
Dosage:10 mg/kg
Administration:P.o.; twice a day (started on days 0, 3, 5, or 7) until day 10
Result:Decreased by approximately 50% the lethality associated with DEN-2 infection.
Animal Model:Male BALB/C (8- to 10- week-old) wild-type mice[5]
Dosage:5, 10 and 20 mg/kg
Administration:P.o.
Result:Dose-dependently inhibited the Zymosan -induced articular hyperalgesia.

Rac-Modipafant Preparation Products And Raw materials

Raw materials

Preparation Products

Rac-Modipafant Suppliers

Global Suppliers ( 31)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Beijing Yisiyan Technology Research Center 010-56645598 13366904824; bjkaida@163.com China 1597 59
AN PharmaTech Co Ltd 86(21)68097365 sales@anpharma.net China 4875 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39866 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chemsky (shanghai) International Co.,Ltd 60
Beijing Yisiyan Technology Research Center 59
AN PharmaTech Co Ltd 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Chongqing Chemdad Co., Ltd 58
Energy Chemical 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from Rac-Modipafant manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(Rac)-Modipafant pictures 2026-07-27 (Rac)-Modipafant
122956-68-7
 $219.00-792.00 98.46% 10g TargetMol Chemicals Inc.
modipafant pictures 2019-07-06 modipafant
122956-68-7
 $7.00 1KG 99% 100KG Career Henan Chemical Co

Rac-Modipafant Spectrum

modipafant(122956-68-7)1HNMR

122956-68-7 (Rac-Modipafant) Related Search:

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2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chlorophenyl)-5-[(2-pyridinylamino)carbonyl]-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester Modipefant UK-74505 4-(2-Chlorophenyl)-1,4-dihydro-6-Methyl-2-[4-(2-Methyl-1H-iMidazo[4,5-c]pyridin-1-yl)phenyl]-5-[(2-pyridinylaMino)carbonyl]-3-pyridinecarboxylic Acid Ethyl Ester rac-Modipafant ethyl 4-(2-chlorophenyl)-6-methyl-2-(4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl)-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate(WXG02205) 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-[(2-pyridinylamino)carbonyl]-, ethyl ester Modipafant racemate (Rac) Modipafant,(Rac)Modipafant ethyl 4-(2-chlorophenyl)-6-methyl-2-(4-{2-methylimidazo[4,5-c]pyridin-1-yl}phenyl)-5-[(pyridin-2-yl)carbamoyl]-1,4-dihydropyridine-3-carboxylate - [AC77674] 122956-68-7 Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals