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ETAZOLATE

ETAZOLATE structure

CAS No.: 51022-77-6

Chemical Name:: ETAZOLATE

Synonyms: ETAZOLATE HYDROCHLORIDE;SQ 20009;SQ 64442;ETAZOLATE;Zinc00001379;Etazolate hydrochlor;1-Ethyl-4-[2-(1-Methylethylidene)hydrazinyl]-;1-Ethyl-4-isopropylidenehydrazino-1H-pyrazolo[3,4-b]-1-pyridine-5-carboxylic Acid Ethyl Ester;1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester;1-Ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester

CBNumber:: CB0140566

Molecular Formula:: C14H19N5O2

Molecular Weight:: 289.33

MDL Number:: MFCD00600136

MOL File:: 51022-77-6.mol

MSDS File:: SDS

Last updated:2026-04-21 10:31:43

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ETAZOLATE Properties

Melting point	193-194°C
Boiling point	427.6±55.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Store at RT
solubility	H₂O: >20 mg/mL Solutions should be freshly prepared.
form	solid
pka	9.94±0.70(Predicted)
color	white
CAS DataBase Reference	51022-77-6
FDA UNII	I89Y79062L

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

ETAZOLATE price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	TRC-E889250-5MG	Etazolate	51022-77-6	5mg	$54	2026-06-03	Buy
Biosynth	FE22846	Etazolate	51022-77-6	1mg	$900	2026-06-04	Buy
Biosynth	FE22846	Etazolate	51022-77-6	10mg	$900	2026-06-04	Buy
Biosynth	FE22846	Etazolate	51022-77-6	5mg	$900	2026-06-04	Buy
Biosynth	FE22846	Etazolate	51022-77-6	2mg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
TRC-E889250-5MG	5mg	$54	Buy
FE22846	1mg	$900	Buy
FE22846	10mg	$900	Buy
FE22846	5mg	$900	Buy
FE22846	2mg	$900	Buy

ETAZOLATE Chemical Properties, Uses, Production

Chemical Properties

Off-White Solid

Uses

PDE inhibitor

Uses

An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP.

Uses

Etazolate Hydrochloride is an acyclic nucleotide phosphodiesterase 4 inhibitor, which also exhibits antidepressant-like activity in acute and chronic mouse and rat model of depression.

Definition

ChEBI: Etazolate is a pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. It has a role as a neuroprotective agent, an antipsychotic agent, a phosphodiesterase IV inhibitor, an anxiolytic drug, an antidepressant, an alpha-secretase activator and a GABA agent. It is a hydrazone, an ethyl ester and a pyrazolopyridine.

Biological Activity

Phosphodiesterase inhibitor, selective for PDE4 (IC 50 = 2.0 μ M).

ETAZOLATE Preparation Products And Raw materials

Raw materials

Preparation Products

ETAZOLATE Suppliers

Global Suppliers ( 59)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8039	58
Shanghai Synchem Pharma Co., ltd	21-619849051-1 18521059765	synchempharma@aliyun.com	China	4988	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Wuhan Chemwish Technology Co.， Ltd	027-67849912	sales@chemwish.com	China	9144	60
Lanzhou Angeli Biochemical Technology Co., Ltd.	0931-8235634 13321316780	1455540579@qq.com	China	957	55

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Wuhan Chemwish Technology Co., Ltd	56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Shanghai TaoSu Biochemical Technology Co., Ltd.	58
Shanghai Synchem Pharma Co., ltd	55
EMMX Biotechnology LLC	60
Wuhan Chemwish Technology Co.， Ltd	60
Lanzhou Angeli Biochemical Technology Co., Ltd.	55

View Latest Price from ETAZOLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	Etazolate 51022-77-6	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

Etazolate
51022-77-6
$1520.00-2500.00
TargetMol Chemicals Inc.

51022-77-6 (ETAZOLATE) Related Search:

4-Amino-3-formylpyridine HCl 4-Aminopyridine-3-carboxylic acid ethyl ester 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-Amino-3-formylpyridine 1H-Pyrazolo[3,4-b]pyridin-4-amine

4-Hydrazinopyridine hydrochloride (4-Amino-pyridin-3-yl)-methanol 4-Amino-3-pyridinecarboxylic acid Methyl 4-aminopyridine-3-carboxylate 3-Methyl-4-aminopyridine

Pyridine, 4-hydrazino-3-methyl- (9CI) ETAZOLATE 4-hydrazinylpyridine hydrochloride

1of3

ETAZOLATE 1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO-[3,4-B]-PYRIDINE-5-CARBOXYLIC ACID, ETHYL ESTER HYDROCHLORIDE 1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER, HCL SQ 20009 1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-β]pyridine-5-carboxylic Acid Ethyl Ester 1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester SQ 64442 1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic Acid Ethyl Ester 1-Ethyl-4-isopropylidenehydrazino-1H-pyrazolo[3,4-b]-1-pyridine-5-carboxylic Acid Ethyl Ester 1-Ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester Zinc00001379 1-Ethyl-4-[2-(1-Methylethylidene)hydrazinyl]- 1-Ethyl-4-(N-isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester hydrochloride 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 1-ethyl-4-[2-(1-methylethylidene)hydrazinyl]-, ethyl ester Etazolate hydrochlor ETAZOLATE HYDROCHLORIDE 51022-77-6 C14H20ClN5O2 C14H20N5O2Cl G Proteins and Cyclic Nucleotides Cyclic Nucleotide Metabolism Phosphodiesterase Inhibitors BioChemical Cell Signaling and Neuroscience Cell Biology All Inhibitors Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Cyclic Nucleotide related