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5-Chloro-2-nitroaniline

5-Chloro-2-nitroaniline Structure
5-Chloro-2-nitroaniline structure
CAS No.
1635-61-6
Chemical Name:
5-Chloro-2-nitroaniline
Synonyms
5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
CBNumber:
CB0141336
Molecular Formula:
C6H5ClN2O2
Molecular Weight:
172.57
MDL Number:
MFCD00007776
MOL File:
1635-61-6.mol
MSDS File:
SDS
Last updated:2026-05-27 17:18:42
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5-Chloro-2-nitroaniline Properties

Melting point 125-129 °C (dec.)(lit.)
Boiling point 200°C (rough estimate)
Density 1.5610 (rough estimate)
refractive index 1.5870 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Chloroform, Methanol
form Liquid
pka -1.46±0.25(Predicted)
color Clear colorless to light yellow
BRN 2210201
InChI InChI=1S/C6H5ClN2O2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H,8H2
InChIKey ZCWXYZBQDNFULS-UHFFFAOYSA-N
SMILES C1(N)=CC(Cl)=CC=C1[N+]([O-])=O
CAS DataBase Reference 1635-61-6(CAS DataBase Reference)
FDA UNII 656XJM4CON
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300+H310+H330-H373-H411
Precautionary statements  P262-P273-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  T+,N,T
Risk Statements  26/27/28-33-51/53
Safety Statements  28-36/37-45-61-28A
RIDADR  UN 2237 6.1/PG 3
WGK Germany  3
F  9-23
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29214210
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 1 Dermal
Acute Tox. 2 Inhalation
Acute Tox. 2 Oral
Aquatic Chronic 2
STOT RE 2
NFPA 704
1
4 0

5-Chloro-2-nitroaniline price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 269050 5-Chloro-2-nitroaniline 97% 1635-61-6 25g $102 2026-04-30 Buy
Sigma-Aldrich 269050 5-Chloro-2-nitroaniline 97% 1635-61-6 5g $55.6 2023-06-20 Buy
TCI Chemical C1139 5-Chloro-2-nitroaniline >99.0%(GC) 1635-61-6 25g $49 2026-04-30 Buy
TCI Chemical C1139 5-Chloro-2-nitroaniline >99.0%(GC) 1635-61-6 250g $236 2026-04-30 Buy
TRC TRC-C373770-5G 5-Chloro-2-nitroaniline 1635-61-6 5g $72 2026-06-03 Buy
Product number Packaging Price Buy
269050 25g $102 Buy
269050 5g $55.6 Buy
C1139 25g $49 Buy
C1139 250g $236 Buy
TRC-C373770-5G 5g $72 Buy

5-Chloro-2-nitroaniline Chemical Properties,Uses,Production

Description

2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.

Preparation

Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.

Chemical Properties

yellow to orange powder

Uses

5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.

Uses

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Application

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

General Description

The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

5-Chloro-2-nitroaniline synthesis

611-06-3
1635-61-6
Synthesis of 5-Chloro-2-nitroaniline from 2,4-Dichloronitrobenzene

5-Chloro-2-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

4-Fluoro-2-nitrobenzonitrile 6-Chloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline 4-Chloro-o-phenylenediamine 2,3,6-Trichloroquinoxaline 6-Chloroquinoxaline
Fenbendazole 2-Amino-5-chlorobenzenesulfonamide Hoechst 33342 3,4-DiaMinodiphenyl ether 5-Chloro-2-nitrophenol
5-(4-Benzylpiperazino)-2-nitroaniline 2-Nitro-5-pyrrolidin-1-yl-phenylamine Benzenamine, 5-[(4-methylphenyl)thio]-2-nitro- Carbamic acid, N-(5-chloro-2-nitrophenyl)-N-methyl-, 1,1-dimethylethyl ester (5-Chloro-2-nitrophenyl)hydrazine
2-[4-(3-Amino-4-nitrophenyl)piperazin-1-yl]ethan-1-ol

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5-Chloro-2-nitroaniline Suppliers

Global( 360)Suppliers
Supplier Tel Email Country ProdList Advantage
Hengshui juming chemical technology co., ltd 13785838008 admin@junrunchem.com China 7 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Hengshui juming chemical technology co., ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60

Related articles

View Lastest Price from 5-Chloro-2-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Chloro-2-nitroaniline pictures 2026-09-12 5-Chloro-2-nitroaniline
1635-61-6
 0.99 RongNa Biotechnology Co.,Ltd
5-Chloro-2-nitroaniline pictures 2026-09-11 5-Chloro-2-nitroaniline
1635-61-6
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
5-Chloro-2-nitroaniline pictures 2026-09-02 5-Chloro-2-nitroaniline
1635-61-6
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd

5-Chloro-2-nitroaniline Spectrum

5-Chloro-2-nitroaniline(1635-61-6)MS5-Chloro-2-nitroaniline(1635-61-6)1HNMR5-Chloro-2-nitroaniline(1635-61-6)13CNMR5-Chloro-2-nitroaniline(1635-61-6)IR15-Chloro-2-nitroaniline(1635-61-6)IR25-Chloro-2-nitroaniline(1635-61-6)Raman

1635-61-6(5-Chloro-2-nitroaniline)Related Search:

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5-Chloro-2-methylaniline 2-Chloroaniline 3-Chloroaniline 4-Nitroaniline 4-CHLORO-2-NITROANILINE
2,5-Dichloroaniline N-Methyl-4-nitroaniline 5-CHLORO-2-NITRODIPHENYLAMINE N1-(5-CHLORO-4-FLUORO-2-NITROPHENYL)ACETAMIDE 5-CHLORO-4-METHYL-2-NITROANILINE
3-CHLORO-2-NITROANILINE Dichlorphenamide bulk powder N1-(4,5-Dichloro-2-nitrophenyl)acetamide

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TIMTEC-BB SBB003828 2-AMINO-4-CHLORO-NITROBENZENE 5-CHLORO-2-NITROANILINE 5-chloro-2-nitro-benzenamin Benzenamine, 5-chloro-2-nitro- 2-NITRO-5-CHLOROANILINE 2-Amino-4-chloro-1-nitrobenzene 5-Chloro-2-nitrophenylamine 5-Chloro-2-nitroaniline ,98% 5-Chloro-2-nitroaniline,97% 5-Chloro-2-nitroaniline, 97% 50GR 5-Chloro-2-nitroaniline, 97% 5GR 5-Chlor-2-nitroanilin 5-CHLORO-2-NITROANILINE 99+% 5-Chloro-2-nitroamiline 5-CHLORO-2-NITROANILINE FOR SYNTHESIS 5-Chloro-2-nitroaniline 97% Aniline, 5-chloro-2-nitro- oro-2-nitroaniL 5-Chloro-2-nitroaniline > 5-Chloro-2-nitroaniline ISO 9001：2015 REACH Atorvastatin Impurity 146 Febantel Impurity: 5-Chloro-2-nitroaniline 5-CHLORO-2-NITROBENZENAMINE 1635-61-6 AMINE Building Blocks Amines C2 to C6 Organic Building Blocks Nitrogen Compounds Pyrimidines API intermediates