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3,4-Dichloroaniline

3,4-Dichloroaniline structure

CAS No.: 95-76-1

Chemical Name:: 3,4-Dichloroaniline

Synonyms: 3,4-dca;3，4-Dichloroanihne;4,5-Dichloroaniline;Gefitinib-1;3.4-Dichloroan;3,4-Dichloroanil;3,4-Dichloranilin;AKOS BBS-00003672;3,4-Dichloraniline;3,4-DICHLOROANILINE

CBNumber:: CB5696598

Molecular Formula:: C6H5Cl2N

Molecular Weight:: 162.02

MDL Number:: MFCD00007768

MOL File:: 95-76-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:48:46

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3,4-Dichloroaniline Properties

Melting point	69-71 °C(lit.)
Boiling point	272 °C(lit.)
Density	1,34 g/cm³
vapor pressure	97.5Pa at 78℃
refractive index	1.6140 (estimate)
Flash point	166 °C
storage temp.	0-6°C
solubility	0.73g/l
pka	2.90±0.10(Predicted)
form	Crystalline Mass and/or Chunks
color	Beige to brown
PH	7.1 (0.8g/l, H2O)
Water Solubility	0.06 g/100 mL
Merck	14,3054
BRN	636837
Henry's Law Constant	6.8×10^-1 mol/(m³Pa) at 25℃, Duchowicz et al. (2020)
Stability	Stable, but darkens in storage. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
InChI	1S/C6H5Cl2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2
InChIKey	SDYWXFYBZPNOFX-UHFFFAOYSA-N
SMILES	Nc1ccc(Cl)c(Cl)c1
LogP	2.68 at 20℃
CAS DataBase Reference	95-76-1(CAS DataBase Reference)
EWG's Food Scores	3-4
FDA UNII	20KR9WJ4NS
NIST Chemistry Reference	Benzenamine, 3,4-dichloro-(95-76-1)
EPA Substance Registry System	3,4-Dichloroaniline (95-76-1)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H301+H311+H331-H315-H318-H371-H372-H317-H334-H410

Precautionary statements

P501-P273-P272-P260-P270-P271-P264-P280-P284-P391-P342+P311-P308+P311-P361+P364-P333+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338+P310-P403+P233-P405

PPE

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes

T,N

Risk Statements

23/24/25-41-43-50/53-51/53-33

Safety Statements

26-36/37/39-45-60-61-36/37-28

RIDADR

UN 1590 (DICHLOROANILINES, LIQUID)

WGK Germany

RTECS

BX2625000

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

HS Code

29214210

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Sens. 1

Hazardous Substances Data

95-76-1(Hazardous Substances Data)

REACH Registrations

Active

Limited Quantities

100ml (liquid) or 0.5 Kg (solid)

Excepted Quantities

Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	1
3		0

3,4-Dichloroaniline price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	437778	3,4-Dichloroaniline 98%	95-76-1	5g	$40	2026-04-30	Buy
Sigma-Aldrich	CRM35827	3,4-Dichloroaniline certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	95-76-1	50MG	$87.8	2026-04-30	Buy
Sigma-Aldrich	437778	3,4-Dichloroaniline 98%	95-76-1	250g	$104	2026-04-30	Buy
Sigma-Aldrich	CRM35827	3,4-Dichloroaniline certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	95-76-1	1 unit	$81.9	2025-07-31	Buy
TCI Chemical	D0324	3,4-Dichloroaniline >98.0%(GC)	95-76-1	25g	$30	2026-04-30	Buy

Product number	Packaging	Price	Buy
437778	5g	$40	Buy
CRM35827	50MG	$87.8	Buy
437778	250g	$104	Buy
CRM35827	1 unit	$81.9	Buy
D0324	25g	$30	Buy

3,4-Dichloroaniline Chemical Properties, Uses, Production

Description

3,4-Dichloroaniline, 1-amino- 3,4- dichlorobenzene, is a gray to dark-brown crystalline solid at room temperature. It is used as an intermediate for pesticides and dyes and is produced by catalytic hydrogenation of 3,4-dichloronitrobenzene with noble metal catalysts under pressure. Various types of additives prevent dehalogenation during production and reactors must be fabricated with special steel alloys to inhibit corrosion .

Chemical Properties

brown solid
3,4-Dichloroaniline

Uses

3,4-Dichloroaniline is used in the preparation of the herbicide propanil (P760840).

Uses

3,4-Dichloroaniline may be employed as derivatization reagent for the HPLC analysis of perfluorooctanoic acid (PFOA).

Uses

3,4-Dichloroaniline is used as an intermediate for pesticides and dyes.

Preparation

3,4-Dichloroaniline is produced by catalytic hydrogenation of 3,4-dichloronitrobenzene with noble metal catalysts under pressure. Various types of additives prevent dehalogenation during production and reactors must be fabricated with special steel alloys to inhibit corrosion.

Definition

ChEBI: A dichloroaniline having the two chloro-substituents at the 3- and 4-positions.

General Description

Light tan to dark gray crystals or brown solid. Melting point 71-72°C.

Air & Water Reactions

Sensitive to prolonged exposure to heat, light and air. Darkens in storage. Insoluble in water.

Reactivity Profile

3,4-Dichloroaniline is incompatible with oxidizing agetns, acids, acid chlorides and acid anhydrides. 3,4-Dichloroaniline can decompose at low pH. Hydrochloric acid accelerates decomposition. Reacts at temperatures above 356°F in the presence of ferric chloride .

Fire Hazard

3,4-Dichloroaniline is combustible.

Metabolic pathway

The basidiomycete Filoboletus sp. TA9054 metabolizes 3,4-dichloroaniline and forms several condensation products on solid media and in liquid culture, and no oligomers are produced. Six metabolites are identified as 3,3'-4,4'- tetrachloroazobenzene, 4-(3,4-dichloroanilino)-3,3',4' - trichloroazobenzene, 4-[(3,4-dichloroanilino)-4-(3,4- dichloroanilino)]-3,3'4'-trichloroazobenzene, 2-(3,4- dichloroanilino)-N-(3,4-dichlorophenyl)-4- (chlorophenylene), 6-(3,4-dichloroanilino)-N-(3,4- dichlorophenyl)-4-(chlorophenylene), and 3,5-bis(3,4- dichloroanilino)-1,4-chlorobenzoquinone.

Purification Methods

Crystallise the aniline from MeOH. [Beilstein 12 IV 1257.]

3,4-Dichloroaniline synthesis

Synthesis of 3,4-Dichloroaniline from 3,4-Dichloronitrobenzene

3,4-Dichloroaniline Preparation Products And Raw materials

Raw materials

4-Chloronitrobenzene Chlorine Ferric chloride Hydrogen Industrial ethanol

3,4-Dichloronitrobenzene 1,2-Dichlorobenzene

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Preparation Products

Propanil 5-[(3,4-dichlorophenyl)azo]-1,2-dihydro-6-hydroxy-1,4-dimethyl-2-oxonicotinonitrile Diuron CHLORANOCRYL 3,4-Dichloro-N-methylaniline

SWEP 1-(3,4-Dichlorophenyl)piperazine Isocyanic acid 3,4-dichlorophenyl ester 2-Amino-5,6-dichlorobenzoic acid 1-(3,4-Dichlorophenyl)-3-methyl urea

3-(3,4-Dichlorophenyl)propionic acid 6-Amino-2H-1,4-benzoxazin-3(4H)-one 1-(3,4-Dichlorophenyl)-2-thiourea 3,3',4,4'-Tetrachloroazobenzene 5,6-Dichloro-2-benzothiazolamine

5-[(3,4-dichlorophenyl)azo]-1,2-dihydro-6-hydroxy-1,4-dimethyl-2-oxonicotinonitrile C.I. Disperse Yellow 58

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3,4-Dichloroaniline Suppliers

Global Suppliers ( 451)

Supplier	Tel	Email	Country	ProdList	Advantage
Alchemie Shanghai Co.,Ltd.	15921545397	info@alchemie-shanghai.com	China	92	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TAIYUAN RHF CO.,LTD.	+86 351 7031519	sales@RHFChem.com	China	2334	56
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66

Supplier	Advantage
Alchemie Shanghai Co.,Ltd.	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TAIYUAN RHF CO.,LTD.	56
TCI (Shanghai) Development Co., Ltd.	81
ShangHai DEMO Chemical Co.,Ltd	57
Energy Chemical	61
Capot Chemical Co., Ltd	66
JinYan Chemicals(ShangHai) Co.,Ltd.	60
Jia Xing Isenchem Co.,Ltd	66

View Latest Price from 3,4-Dichloroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	3,4-Dichloroaniline 95-76-1		20kg	99%	20 tons	Qingdao RENAS Polymer Material Co., Ltd.
2026-03-20	3,4-Dichloroaniline 95-76-1	$10.00	1KG	99%	5tons	Hebei Chuanghai Biotechnology Co., Ltd
2023-10-08	3,4-Dichloroaniline 95-76-1	$30.00	1KG	99%	20T	Firsky International Trade (Wuhan) Co., Ltd

3,4-Dichloroaniline
95-76-1
$0.00
99%
Qingdao RENAS Polymer Material Co., Ltd.

3,4-Dichloroaniline
95-76-1
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

3,4-Dichloroaniline
95-76-1
$30.00
99%
Firsky International Trade (Wuhan) Co., Ltd

3,4-Dichloroaniline Spectrum

3,4-Dichloroaniline(95-76-1)MS 3,4-Dichloroaniline(95-76-1)¹HNMR 3,4-Dichloroaniline(95-76-1)¹³CNMR 3,4-Dichloroaniline(95-76-1)IR1 3,4-Dichloroaniline(95-76-1)IR2 3,4-Dichloroaniline(95-76-1)IR3 3,4-Dichloroaniline(95-76-1)Raman

95-76-1 (3,4-Dichloroaniline) Related Search:

2-Chloroaniline Betaine 3-Chloroaniline 1,2-Dichlorobenzene 4-Chloroaniline

1,4-Dichlorobenzene Glycine Aminoethoxyvinyl glycine hydrochloride 4-(3-Chloropropyl)morpholine Gefitinib-d6

Gefitinib Impurity 11 Gefitinib Chloro Impurity 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Gefitinib Impurity 8 O-Desmorpholinopropyl Gefitinib

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one 4-Methoxy-5-[3-(4-morpholinyl)propoxy]-2-nitrobenzonitrile Gefitinib 3,4-Difluoro Impurity HCl

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3,4-DICHLOROPHENYLAMINE 3,4-dichlorobenzenamine 3,4-DICHLOROANILINE 3,4-Dichloranilin 3,4-Dichloraniline 3,4-Dichloroanaline 3,4-dichloro-anilin 3,4-dichloro-benzenamin Aniline, 3,4-dichloro- LABOTEST-BB LTBB000652 1-AMINO-3,4-DICHLORO-BENZENE Gefitinib Impurity 25 Gefitinib-1 Gefitinib Impurity 3 3,4-Dichloroanil high quality 3,4-Dichloroanilinekf-wang(at)kf-chem.com m,p-dichloroaniline AKOS BBS-00003672 Benzenamine, 3,4-dichloro- 3,4-DICHLOROANILINE PESTANAL 3,4-Dichloroaniline,>98% 3,4-DichloroAniline(3,4-Dca)99.5% 3,4-dichloroaminobenzene) 3,4-DICHLOROBENZAMINE DICHLORO-3,4-ANILINE 3,4-Dichlorobenzeneamine 3,4-Dichloroaniline, 98% 250GR 3,4-Dichloroaniline, 98% 5GR 3, 4-2 chloro aniline 3.4-Dichloroan Gefitinib IMpurity III 3,4-DichloroanilineSolution,1,000mg/L,1ml 3,4-Dichloroaniline > 3,4-DichloroanilineSolution,100mg/L,1ml 3,4-Dichloroaniline ISO 9001：2015 REACH 3-OXO-3-P-TOLYL-PROPIONI 3,4-Dichloroaniline,99% 3，4-Dichloroaniline in methanol Dichloroaniline (15 mg) (3,4-Dichloroaniline) 3,4-Dichloroaniline Solution in Toluene 3,4-Dichloroaniline 100 μg/ml Methanol 3,4-Dichloroaniline 100 μg/ml Toluene C12323400 3,4-Dichloroaniline XA12323400AL3,4-DichloroanilinE100μg/mLin Ac 3,4-Dichloroaniline 100 μg/mL in Acetonitrile 3，4-Dichloroanihne 3,4-dca 4,5-Dichloroaniline 95-76-1 122-51-4 Building Blocks Amines C2 to C6 Nitrogen Compounds Organic Building Blocks amine | alkyl chloride Aromatics Miscellaneous Reagents